NFE2

Gene Symbol	NFE2
Entrez Gene	4778
Alt Symbol	NF-E2, p45
Species	Human
Gene Type	protein-coding
Description	nuclear factor, erythroid 2
Other Description	leucine zipper protein NF-E2|nuclear factor (erythroid-derived 2), 45kD|nuclear factor (erythroid-derived 2), 45kDa|nuclear factor, erythroid-derived 2 45 kDa subunit|p45 NF-E2|transcription factor NF-E2 45 kDa subunit
Swissprots	Q6ICV9 Q16621 Q07720
Accessions	ABC79302 CCQ43105 CCQ77681 EAW96771 EAW96772 EAW96773 Q16621 AK290555 BAF83244 AK290564 BAF83253 AK313207 BAG36023 BC005044 AAH05044 BE243330 BT007288 AAP35952 BX406317 CR450284 CAG29280 DQ893437 ABM84363 DQ896796 ABM87795 EU176417 ABW03868 GD141614 GU068583 ACY92458 L13974 AAA35612 L24122 AAA16118 S77763 AAB34115 XM_005268906 XP_005268963 XM_011538397 XP_011536699 NM_001136023 NP_001129495 NM_001261461 NP_001248390 NM_006163 NP_006154
Function	Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron. {ECO:0000269|PubMed:11154691, ECO:0000269|PubMed:16287851}.
Subcellular Location	Nucleus, PML body. Cytoplasm. Note=The sumoylated form locates to the nuclear bodies PML oncogenic domains (PODs). Translocated to the cytoplasm through interaction with ITCH.
Tissue Specificity	Expressed in hematopoietic cells and also in colon and testis.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NF-E2 (D-6) - sc-365083 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

NF-E2 (G-2) - sc-514429 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

NF-E2 (H-230) - sc-22827 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

NF-E2 (C-19) - sc-291 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-Nuclear Factor Erythroid Derived 2 antibody - ab154605 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Nuclear Factor Erythroid Derived 2 antibody - ab77321 from Abcam Prices $376.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-Nuclear Factor Erythroid Derived 2 antibody - ab116057 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Nuclear Factor Erythroid Derived 2 antibody [EPR2824(2)] - ab140598 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR2824(2)

Anti-NFE2 / p45 Antibody (aa311-340, AP) - LS-C264279 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NFE2 / p45 Antibody (aa311-340, APC) - LS-C264281 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NFE2 / p45 Antibody (aa311-340, Biotin) - LS-C264282 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NFE2 / p45 Antibody (aa311-340, PE) - LS-C264285 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NFE2 / p45 Antibody (aa311-340, FITC) - LS-C264283 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NFE2 / p45 Antibody (aa311-340, Azide-free, HRP) - LS-C264284 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NFE2 / p45 Antibody (aa311-340) - LS-C329889 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-NFE2 / p45 Antibody (aa108-157) - LS-C102741 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-NFE2 / p45 Antibody (N-Terminus) - LS-C134925 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-NFE2 / p45 Antibody (aa312-340) - LS-C164843 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-NFE2 / p45 Antibody (aa311-360) - LS-C205639 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-NFE2 / p45 Antibody (clone 2C6) - LS-C197774 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2C6

Nuclear Factor Erythroid Derived 2 Antibody - NBP1-82580 from Novus Biologicals Prices $129.00, $419.00 Sizes 25 µl, 100 µl Host Rabbit Clonality Polyclonal

Nuclear Factor Erythroid Derived 2 Antibody - NBP1-31540 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Nuclear Factor Erythroid Derived 2 Antibody - NBP1-69226 from Novus Biologicals Prices $369.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Nuclear Factor Erythroid Derived 2 Antibody (2C6) - H00004778-M01 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2C6

Anti-NFE2 antibody produced in rabbit - HPA001914 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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