Grem1

Gene Symbol	Grem1
Entrez Gene	23892
Alt Symbol	Cktsf1b1, Drm, Grem, ld
Species	Mouse
Gene Type	protein-coding
Description	gremlin 1
Other Description	cysteine knot superfamily 1, BMP antagonist 1|down-regulated in Mos-transformed cells protein|down-regulated in v-mos-transformed cells|gremlin-1
Swissprots	O70326
Accessions	AAD54057 EDL27855 O70326 AF045801 AAC40111 AF108189 AAD54056 AK080776 AK135022 BAE22388 AK148693 AK157737 AK157793 BAE34201 AK164871 BAE37950 BC015293 AAH15293 BY151119 XM_006499444 XP_006499507 NM_011824 NP_035954
Function	Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Acts as inhibitor of monocyte chemotaxis. {ECO:0000269|PubMed:12808456, ECO:0000269|PubMed:15133038, ECO:0000269|PubMed:15201225}.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Highly expressed in spleen and to a lesser extent in lung, skeletal muscle and kidney. Expressed only in non- transformed cells or primary fibroblasts in culture but not in established transformed or tumor derived cell lines. Broadly expressed in limb bud mesenchyme but restricted to the distal limb bud mesenchyme and concentrated posteriorly. Expressed in ovary especially in granulosa cells of follicles of type 4. {ECO:0000269|PubMed:10965135, ECO:0000269|PubMed:12808456, ECO:0000269|PubMed:15133038}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Gremlin 1 (GREM1), Mouse, ELISA Kit - SEC128Mu from ARP American Research Products Category ELISA Kit Prices $740.00 Sizes 96 t Sensitivity 0.061ng/mL Range 0.156-10ng/mL

Gremlin 1, Mouse, ELISA Kit - E03G0253 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0 pg/mL, Range 250-5000pg/mL,

Gremlin-1 (GREM1), Mouse, ELISA Kit - CSB-EL009892MO from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Gremlin-1, Grem1, Mouse, ELISA Kit - E2130m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Mouse Gremlin-1 ELISA - ELM-GREM1 from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,561.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 0.8 ng/ml Range 0.8 ng/ml - 200 ng/ml

Mouse GREM1 ELISA Kit - MG0260 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Gremlin 1 (GREM1), ELISA Kit - MBS2020142 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 57pg/mL. Range 125-8,000pg/mL.

Gremlin 1 (GREM1), ELISA Kit - MBS2023766 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.061ng/mL. Range 0.156-10ng/mL

gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) , ELISA Kit - MBS919128 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 23.44 pg/ml. Range 93.75 pg/ml-6000 pg/ml.

Mouse GREM1(GremLin 1) ELISA Kit - E-EL-M0595 from Elabscience Category ELISA Kit Sensitivity 46.88 pg/mL Range 78.13—5000 pg/mL

Mouse GREM1 (GremLin 1) CLIA Kit - E-CL-M0360 from Elabscience Category CLIA Kit Sensitivity 9.38 pg/mL Range Average Recovery (%)

Mouse Gremlin-1(GREM1) ELISA kit - CSB-EL009892MO from Cusabio Category ELISA Kit Sensitivity 23.44 pg/ml Range 93.75 pg/ml-6000 pg/ml

ELISA Kit for Gremlin 1 (GREM1) - SEC128Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.067ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mouse Gremlin 1 (GREM1) ELISA Kit - EKU04573 from Biomatik Category ELISA Kit Prices $756.00, $3,326.00, $6,048.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.061 ng/mL Range 0.156-10 ng/mL

Mouse GREM1(GremLin 1) ELISA Kit - E-EL-M0595 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 46.88 pg/mL Range 78.13~5000 pg/mL

Mouse CCKAR (Cholecystokinin A Receptor) CLIA Kit - E-CL-M0191 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Mouse GREM1 (GremLin 1) CLIA Kit - E-CL-M0360 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 46.875pg/mL Range 78.125-5000pg/mL

Mouse Gremlin 1 ELISA Kit - abx154112 from Abbexa Category ELISA Kit Sensitivity 0.061 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mouse Gremlin-1 ELISA Kit - abx255076 from Abbexa Category ELISA Kit Range 78.125 pg/ml - 5000 pg/ml

Gremlin 1 (GREM1), Mouse, ELISA Kit - DL-GREM1-Mu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Range 0.156-10 ng/mL

GREM1 (GremLin 1), CLIA Kit - MBS2530819 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

GREM1 (Gremlin 1), CLIA Kit - MBS2530576 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

GREM1 (GremLin 1), CLIA Kit - MBS2532442 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

Mouse GREM1 ELISA Kit - abx571065 from Abbexa Category ELISA Kit Sensitivity 0.061 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mouse Gremlin-1 ELISA Kit - RAB1124 from Sigma-Aldrich Category ELISA Kit Prices $390.00 Sizes 1 kt Sensitivity 0.8 ng/ml

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