Grem1

Gene Symbol	Grem1
Entrez Gene	23892
Alt Symbol	Cktsf1b1, Drm, Grem, ld
Species	Mouse
Gene Type	protein-coding
Description	gremlin 1
Other Description	cysteine knot superfamily 1, BMP antagonist 1|down-regulated in Mos-transformed cells protein|down-regulated in v-mos-transformed cells|gremlin-1
Swissprots	O70326
Accessions	AAD54057 EDL27855 O70326 AF045801 AAC40111 AF108189 AAD54056 AK080776 AK135022 BAE22388 AK148693 AK157737 AK157793 BAE34201 AK164871 BAE37950 BC015293 AAH15293 BY151119 XM_006499444 XP_006499507 NM_011824 NP_035954
Function	Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Acts as inhibitor of monocyte chemotaxis. {ECO:0000269|PubMed:12808456, ECO:0000269|PubMed:15133038, ECO:0000269|PubMed:15201225}.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Highly expressed in spleen and to a lesser extent in lung, skeletal muscle and kidney. Expressed only in non- transformed cells or primary fibroblasts in culture but not in established transformed or tumor derived cell lines. Broadly expressed in limb bud mesenchyme but restricted to the distal limb bud mesenchyme and concentrated posteriorly. Expressed in ovary especially in granulosa cells of follicles of type 4. {ECO:0000269|PubMed:10965135, ECO:0000269|PubMed:12808456, ECO:0000269|PubMed:15133038}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GREMLIN-Antibody-C-term-Blocking-Peptide - BP6133a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Mouse Gremlin - 956-GR-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Lys25-Asp184, with a C-terminal 10-His tag

Recombinant Mouse Gremlin, CF - 956-GR-050/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Lys25-Asp184, with a C-terminal 10-His tag

Mouse GREM1 protein (His Tag) - orb138952 from Biorbyt Category Protein Prices $162.00, $400.00, $612.00 Sizes 5 μg, 50 μg, 100 μg Source Baculovirus-Insect Cells Species Mouse

Mouse Gremlin 1 Protein - abx066923 from Abbexa Category Protein Source E.coli Species Mouse

Gremlin-1 / GREM1 - AR26008PU-N from Acris Antibodies Category Protein Prices $255.00 Sizes 50 µg Source E. coli Species Mouse

Gremlin 1 (GREM1), Mouse - 20-8372 from ARP American Research Products Category Protein Prices $419.00 Sizes 50 µg Source E.coli Species Mouse

Recombinant Mouse Grem1, His-tagged - Grem1-1011M from Creative Biomart Category Protein Source NSO Cells Species Mouse

Recombinant Mouse Gremlin 1, His-tagged - Grem1-5635M from Creative Biomart Category Protein Source Murine myeloma cellline, NS0-derived.

Mouse Gremlin 1 / GREM1 Protein (His Tag) - 50016-M08B-50 from Sino Biological Category Protein Source Baculovirus-Insect Cells Species Mouse

Recombinant Gremlin 1 (GREM1) - RPC128Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Gremlin 1 (GREM1) - RPC128Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Gremlin-1(Grem1) - CSB-YP009892MO CSB-EP009892MO CSB-BP009892MO CSB-MP009892MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Gremlin-1, human recombinant - 7159-10 from Biovision Category Protein Prices $85.00 Sizes 10 μg Source CHO cells Species Human

Gremlin-1, human recombinant - 7159-50 from Biovision Category Protein Prices $285.00 Sizes 50 μg Source CHO cells Species Human

Recombinant Mouse Gremlin Protein, CF - 956-GR/CF from R&D Systems Category Protein Prices $339.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Lys25-Asp184, with a C-terminal 10-His tag Species Mouse

Recombinant Mouse Gremlin Protein - 956-GR from R&D Systems Category Protein Prices $339.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Lys25-Asp184, with a C-terminal 10-His tag Species Mouse

Gremlin 1 (GREM1) - RPU141746 from Biomatik Category Protein Prices $192.50, $385.00, $577.50 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Mouse

Recombinant Mouse Gremlin-1 - CS417 from Cell Science Prices $295.00 Sizes 50 μg Species Mouse

Recombinant Mouse Gremlin 1 / GREM1 Protein (His tag) - PKSM040914 from Elabscience Category Protein Source Baculovirus-Insect Cells Species Mouse

Gremlin-1, human recombinant - 7159 from Biovision Category Protein Prices $85.00, $285.00 Sizes 10 μg, 50 μg Source CHO cells Species Human

Human CellExp™ Gremlin / GREM1, Fc Tag, Human recombinant - P1123 from Biovision Category Protein Prices $95.00, $395.00 Sizes 10 μg, 50 μg Source HEK 293 cells Species Human

Human CellExp™ Gremlin / GREM1, Human recombinant - P1124 from Biovision Category Protein Prices $95.00, $395.00 Sizes 10 μg, 50 μg Source HEK 293 cells Species Human

Recombinant Gremlin 1 (GREM1) - RPU41746 from Biomatik Category Protein Prices $182.00, $315.00, $482.00, $602.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Mouse

GREM1 Recombinant Protein (OPCD03677) - OPCD03677 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

Search more