Grem1

Gene Symbol Grem1
Entrez Gene 23892
Alt Symbol Cktsf1b1, Drm, Grem, ld
Species Mouse
Gene Type protein-coding
Description gremlin 1
Other Description cysteine knot superfamily 1, BMP antagonist 1|down-regulated in Mos-transformed cells protein|down-regulated in v-mos-transformed cells|gremlin-1
Swissprots O70326
Accessions AAD54057 EDL27855 O70326 AF045801 AAC40111 AF108189 AAD54056 AK080776 AK135022 BAE22388 AK148693 AK157737 AK157793 BAE34201 AK164871 BAE37950 BC015293 AAH15293 BY151119 XM_006499444 XP_006499507 NM_011824 NP_035954
Function Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Acts as inhibitor of monocyte chemotaxis. {ECO:0000269|PubMed:12808456, ECO:0000269|PubMed:15133038, ECO:0000269|PubMed:15201225}.
Subcellular Location Secreted {ECO:0000305}.
Tissue Specificity Highly expressed in spleen and to a lesser extent in lung, skeletal muscle and kidney. Expressed only in non- transformed cells or primary fibroblasts in culture but not in established transformed or tumor derived cell lines. Broadly expressed in limb bud mesenchyme but restricted to the distal limb bud mesenchyme and concentrated posteriorly. Expressed in ovary especially in granulosa cells of follicles of type 4. {ECO:0000269|PubMed:10965135, ECO:0000269|PubMed:12808456, ECO:0000269|PubMed:15133038}.

gremlin-1 CRISPR/Cas9 KO Plasmid (m) - sc-423885 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

gremlin-1 HDR Plasmid (m) - sc-423885-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

gremlin-1 Double Nickase Plasmid (m) - sc-423885-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

gremlin-1 Double Nickase Plasmid (m2) - sc-423885-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

gremlin-1 CRISPR Activation Plasmid (m) - sc-423885-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

gremlin-1 CRISPR Activation Plasmid (m2) - sc-423885-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

gremlin-1 Lentiviral Activation Particles (m) - sc-423885-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

gremlin-1 Lentiviral Activation Particles (m2) - sc-423885-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

gremlin-1 siRNA (m) - sc-39409 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

gremlin-1 shRNA Plasmid (m) - sc-39409-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

gremlin-1 shRNA (m) Lentiviral Particles - sc-39409-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU051841 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN32825 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND32825 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GREM1 siRNA (Mouse) - CRM4569 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

GREM1 - MBS8230415 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse GREM1 (NM_011824.4) - SHH307654 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse Gremlin 1 siRNA - orb284045 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

GREM1 shRNA Plasmid (Mouse) - CHM4569 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
Search more