TNFAIP8

Gene Symbol	TNFAIP8
Entrez Gene	25816
Alt Symbol	GG2-1, MDC-3.13, NDED, SCC-S2, SCCS2
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor, alpha-induced protein 8
Other Description	NF-kappa-B-inducible DED-containing protein|TNF alpha-induced protein 8|TNF-induced protein GG2-1|head and neck tumor and metastasis-related protein|tumor necrosis factor alpha-induced protein 8
Swissprots	Q9P1Q1 B3KMH1 B7Z713 B3KMI2 O95379 Q9UP47 Q9UER5
Accessions	EAW48913 EAW48914 O95379 AF070671 AAC83229 AF098933 AAF29435 AF098934 AF099935 AAC72975 AF099936 AAC72976 AK001850 BAG50983 AK001931 BAG50994 AK097284 BAG53444 AK097884 AK301281 BAH13449 BC005352 AAH05352 BC007014 AAH07014 BE958495 BP274520 CB241243 CR457137 CAG33418 DA278032 DB114867 DB124282 DC391074 HQ448379 ADQ32859 NM_001077654 NP_001071122 NM_001286813 NP_001273742 NM_001286814 NP_001273743 NM_001286815 NP_001273744 NM_001286817 NP_001273746 NM_014350 NP_055165
Function	Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. {ECO:0000269|PubMed:10644768, ECO:0000269|PubMed:11346652, ECO:0000269|PubMed:14724590}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:14724590}.
Tissue Specificity	Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine- activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle. {ECO:0000269|PubMed:10233894, ECO:0000269|PubMed:10644768, ECO:0000269|PubMed:14724590}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TNFAIP8-Over-expression-Lysate - LY13912a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

TNFAIP8 293T Cell Transient Overexpression Lysate(Denatured) - H00025816-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

TNFAIP8 overexpression lysate - LY402318 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

TNFAIP8 overexpression lysate - LY421470 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

TNFAIP8 overexpression lysate - LY425876 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

TNFAIP8 293 Cell Lysate - 402036 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Disease Tumor

TNFAIP8 Overexpression Lysate (Denatured) - H00025816-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

TNFAIP8 Overexpression Lysate (Native) - NBL1-17138 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TNF-IP 8 (h): 293T Lysate - sc-371558 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

TNFAIP8 Over-expression Lysate Product - GWB-3A75DC from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human TNFAIP8 Knockdown Stable Cell Line - CSC-DC016345 from Creative biogene Category Cell Line Species Human

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