TNFAIP8

Gene Symbol	TNFAIP8
Entrez Gene	25816
Alt Symbol	GG2-1, MDC-3.13, NDED, SCC-S2, SCCS2
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor, alpha-induced protein 8
Other Description	NF-kappa-B-inducible DED-containing protein|TNF alpha-induced protein 8|TNF-induced protein GG2-1|head and neck tumor and metastasis-related protein|tumor necrosis factor alpha-induced protein 8
Swissprots	Q9P1Q1 B3KMH1 B7Z713 B3KMI2 O95379 Q9UP47 Q9UER5
Accessions	EAW48913 EAW48914 O95379 AF070671 AAC83229 AF098933 AAF29435 AF098934 AF099935 AAC72975 AF099936 AAC72976 AK001850 BAG50983 AK001931 BAG50994 AK097284 BAG53444 AK097884 AK301281 BAH13449 BC005352 AAH05352 BC007014 AAH07014 BE958495 BP274520 CB241243 CR457137 CAG33418 DA278032 DB114867 DB124282 DC391074 HQ448379 ADQ32859 NM_001077654 NP_001071122 NM_001286813 NP_001273742 NM_001286814 NP_001273743 NM_001286815 NP_001273744 NM_001286817 NP_001273746 NM_014350 NP_055165
Function	Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. {ECO:0000269|PubMed:10644768, ECO:0000269|PubMed:11346652, ECO:0000269|PubMed:14724590}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:14724590}.
Tissue Specificity	Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine- activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle. {ECO:0000269|PubMed:10233894, ECO:0000269|PubMed:10644768, ECO:0000269|PubMed:14724590}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TNFAIP8 full length protein - ab156983 from Abcam Category Protein Source E. coli Species Human

Human TNFAIP8 full length protein - ab161798 from Abcam Category Protein Source Wheat germ Species Human

TNFAIP8 / SCC-S2 Antibody Blocking Peptide - LS-E631 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TNFAIP8 Recombinant Protein - H00025816-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human TNFAIP8 Protein - NBP2-22908 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

TNFAIP8-Antibody-N-term-Blocking-peptide - BP10969a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNFAIP8 Protein - GTX111940-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

Human TNFAIP8 protein - orb191286 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli Species Human

Human TNF-IP 8 protein - orb139760 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Human TNFAIP8 protein - orb245526 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

TNFAIP8 peptide - orb218459 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Cat

TNFAIP8 protein (His tag) - 80R-2855 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

SCC-S2 Blocking Peptide - abx063790 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Pig

TNFAIP8 (1-198, His-tag) - AR50974PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

TNFAIP8 (1-198, His-tag) - AR50974PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

TNFAIP8 - H00025816-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TNFAIP8 - H00025816-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TNFAIP8, 1-198aa, Human, His tag, E.coli - 01-P2150 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

TNFAIP8 fusion protein - Ag8805 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

TNFAIP8 fusion protein - Ag8491 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human TNFAIP8, His-tagged - TNFAIP8-7639H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human TNFAIP8, His tagged - TNFAIP8-535H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human TNFAIP8, His-tagged - TNFAIP8-3316H from Creative Biomart Category Protein Source E.coli Species Human

Human TNFAIP8 Protein (His Tag) - 14559-H07E-20 from Sino Biological Category Protein Prices $138.00, $138.00 Sizes 20 µg, 100 µg Source E. coli Species Human

SCC-S2 Blocking Peptide - CBP2596 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Chicken, Pig

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