MCM5

Gene Symbol	MCM5
Entrez Gene	4174
Alt Symbol	CDC46, P1-CDC46
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex component 5
Other Description	CDC46 homolog|DNA replication licensing factor MCM5|MCM5 minichromosome maintenance deficient 5, cell division cycle 46|minichromosome maintenance deficient 5 (cell division cycle 46)
Swissprots	Q9BTJ4 O60785 P33992 Q14578 Q9BWL8
Accessions	AAO21127 CBX85478 EAW60060 EAW60061 EAW60062 EAW60063 P33992 AB209612 BAD92849 AK122853 BAG53762 AK130620 AK223323 BAD97043 AK291136 BAF83825 AK298624 BAG60801 AK301121 BAG62717 AK308343 AK312533 BAG35432 BC000142 AAH00142 BC003656 AAH03656 BM787690 CR456517 CAG30403 CU013117 CAK54548 CU013405 CAK54847 D83986 BAA12176 X74795 CAA52802 XM_006724242 XP_006724305 NM_006739 NP_006730
Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP. {ECO:0000250}.
Subcellular Location	Nucleus.
Top Pathways	DNA replication, Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MCM5 full length protein - ab131918 from Abcam Category Protein Source Wheat germ Species Human

MCM5 Antibody Blocking Peptide - LS-E27812 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM5 Antibody Blocking Peptide - LS-E27813 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM5 Antibody Blocking Peptide - LS-E13145 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MCM5 Protein - H00004174-P01 from Novus Biologicals Category Protein Prices $319.00, $529.00 Sizes 2 µg, 25 µg Source Wheat Germ Species Human

MCM5 Blocking Peptide - 33R-6425 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CDC46 Blocking Peptide - abx062924 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Monkey, Rabbit

MCM5 Peptide - AC21-2623-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MCM5 Peptide - AC21-2624-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MCM5 - H00004174-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

MCM5 fusion protein - ag2271 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MCM5, His-tagged - MCM5-28041TH from Creative Biomart Category Protein Source E. coli

Recombinant Minichromosome Maintenance Deficient 5 (MCM5) - RPE651Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

CDC46 Blocking Peptide - CBP1730 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Chicken, Monkey, Rabbit

MCM5 (F51) Peptide - BS1222P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Minichromosome Maintenance Deficient 5 (MCM5) - RPE651Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human DNA replication licensing factor MCM5(MCM5) - CSB-YP013595HU CSB-EP013595HU CSB-BP013595HU CSB-MP013595HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MCM5 Protein - NBP1-85722PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MCM5 Blocking Peptide (OESA09459) - OESA09459 from Aviva Systems Biology Category Peptide Prices $245.00 Sizes 50 µg Species Human

MCM5-Antibody-N-term-Blocking-peptide - BP10094a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MCM5-Antibody-C-term-Blocking-Peptide - BP9078b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MCM5 Peptide, Human - M34GP09317H from Creative Peptides Category Peptide Source Synthetic. Species Human

MCM5 Recombinant Protein (OPCD05174) - OPCD05174 from Aviva Systems Biology Category Protein Source E.coli Species Human

DNA replication licensing factor MCM5 (MCM5), Recombinant Protein - MBS957605 from MyBioSource Category Protein Prices $1,545.00, $1,545.00, $1,770.00, $1,770.00, $2,655.00, $2,655.00, $3,095.00, $3,095.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Minichromosome Maintenance Deficient 5, Recombinant Protein - MBS2029152 from MyBioSource Category Protein Prices $190.00, $395.00, $610.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

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