MCM5

Gene Symbol MCM5
Entrez Gene 4174
Alt Symbol CDC46, P1-CDC46
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex component 5
Other Description CDC46 homolog|DNA replication licensing factor MCM5|MCM5 minichromosome maintenance deficient 5, cell division cycle 46|minichromosome maintenance deficient 5 (cell division cycle 46)
Swissprots Q9BTJ4 O60785 P33992 Q14578 Q9BWL8
Accessions AAO21127 CBX85478 EAW60060 EAW60061 EAW60062 EAW60063 P33992 AB209612 BAD92849 AK122853 BAG53762 AK130620 AK223323 BAD97043 AK291136 BAF83825 AK298624 BAG60801 AK301121 BAG62717 AK308343 AK312533 BAG35432 BC000142 AAH00142 BC003656 AAH03656 BM787690 CR456517 CAG30403 CU013117 CAK54548 CU013405 CAK54847 D83986 BAA12176 X74795 CAA52802 XM_006724242 XP_006724305 NM_006739 NP_006730
Function Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP. {ECO:0000250}.
Subcellular Location Nucleus.
Top Pathways DNA replication, Cell cycle

MCM5 CRISPR/Cas9 KO Plasmid (h) - sc-401980 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM5 HDR Plasmid (h) - sc-401980-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM5 Double Nickase Plasmid (h) - sc-401980-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM5 Double Nickase Plasmid (h2) - sc-401980-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM5 CRISPR Activation Plasmid (h) - sc-401980-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM5 CRISPR Activation Plasmid (h2) - sc-401980-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM5 Lentiviral Activation Particles (h) - sc-401980-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM5 Lentiviral Activation Particles (h2) - sc-401980-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM5 siRNA (h) - sc-35883 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCM5 shRNA Plasmid (h) - sc-35883-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCM5 shRNA (h) Lentiviral Particles - sc-35883-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU012361 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13122 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13122 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01358 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01358

MCM5 siRNA (Human) - CRH2842 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MCM5 RNAi - H00004174-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MCM5 (NM_006739.3) - SHH339323 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MCM5(NM_006739.3) - SHH181415 from Creative biogene

Category siRNA
Species Reactivities Human

MCM5 shRNA Plasmid (Human) - CHH2842 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MCM5 miRNA 3'UTR clone - MiUTR1H-06164 from Creative biogene

Species Reactivities Human
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