KRT17

Gene Symbol	KRT17
Entrez Gene	3872
Alt Symbol	K17, PC, PC2, PCHC1
Species	Human
Gene Type	protein-coding
Description	keratin 17, type I
Other Description	39.1|CK-17|cytokeratin-17|keratin 17 epitope S1|keratin 17 epitope S2|keratin 17 epitope S4|keratin, type I cytoskeletal 17|keratin-17
Swissprots	A5Z1N0 A6NKQ2 Q6IP98 A6NDV6 A5Z1M9 Q8N1P6 A5Z1N1 A5Z1N2 Q04695
Accessions	AAB34565 AAD15003 CAA79626 EAW60750 EAW60751 EAW60752 EAW60753 Q04695 AK095342 BAC04534 AK304373 BAG65211 BC000159 AAH00159 BC011901 AAH11901 BC056421 AAH56421 BC072018 AAH72018 BC072019 AAH72019 BP226061 BX647923 DQ891101 ABM82027 DQ894283 ABM85209 EF608068 ABQ96595 EF608069 ABQ96596 EF608070 ABQ96597 EF608071 ABQ96598 X05803 CAA29248 X62571 CAA44451 NM_000422 NP_000413
Function	Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions bein
Subcellular Location	Cytoplasm {ECO:0000250|UniProtKB:Q9QWL7}.
Tissue Specificity	Expressed in the outer root sheath and medulla region of hair follicle specifically from eyebrow and beard, digital pulp, nail matrix and nail bed epithelium, mucosal stratified squamous epithelia and in basal cells of oral epithelium, palmoplantar epidermis and sweat and mammary glands. Also expressed in myoepithelium of prostate, basal layer of urinary bladder, cambial cells of sebaceous gland and in exocervix (at protein level). {ECO:0000269|PubMed:10651700, ECO:0000269|PubMed:10844551, ECO:0000269|PubMed:1281771, ECO:0000269|PubMed:2481679}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Cytokeratin 17 full length protein - ab116974 from Abcam Category Protein Source Wheat germ Species Human

Human Cytokeratin 17 full length protein - ab177718 from Abcam Category Protein Source E. coli Species Human

Cytokeratin 17 Recombinant Protein - H00003872-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

KRT17-Antibody-C-term-Blocking-peptide - BP13426b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

cytokeratin-17 protein - orb197657 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

Cytokeratin 17 Blocking Peptide - 33R-3900 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

KRT17 protein (His tag) - 80R-3713 from Fitzgerald Category Protein Prices $375.00 Sizes 100 µg Source E.coli

Human Keratin 17 Protein - abx067611 from Abbexa Category Protein Source E.coli Species Human

Cytokeratin 17 (1-432, His-tag) - AR51400PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 500 µg Source E. coli Species Human

Cytokeratin 17 (1-432, His-tag) - AR51400PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

Cytokeratin 17 (1-433) - H00003872-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Cytokeratin 17 (1-433) - H00003872-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human cytokeratin-17 - 230-00561-10 from RayBiotech Category Protein Prices $110.00 Sizes 10 µg Source Escherichia coli (E.coli) Species Human

Recombinant human cytokeratin-17 - 230-00561-50 from RayBiotech Category Protein Prices $224.00 Sizes 50 µg Source Escherichia coli (E.coli) Species Human

Recombinant human cytokeratin-17 - 230-00561-100 from RayBiotech Category Protein Prices $336.00 Sizes 100 µg Source Escherichia coli (E.coli) Species Human

Keratin 17 (KRT17), Human - 20-8055 from ARP American Research Products Category Protein Prices $449.00 Sizes 50 µg Source E.coli Species Human

KRT17, 1-432aa Human, His tag, E.coli - 01-P2580 from ARP American Research Products Category Protein Prices $189.00, $449.00, $1,089.00 Sizes 20 µg, 50 µg, 500 µg Species Human

KRT17 fusion protein - ag13351 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

KRT17 fusion protein - Ag17657 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

KRT17 fusion protein - ag17575 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human KRT17, His-tagged - KRT17-5084H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human keratin 17, His-tagged - KRT17-483H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Keratin 17 (KRT17) - RPB822Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Keratin 17 (KRT17) - RPB822Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Cytokeratin 17 Blocking Peptide - CBP1664 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Rat, Dog, Rabbit

Search more