Gene Symbol | TTI2 |
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Entrez Gene | 80185 |
Alt Symbol | C8orf41, MRT39 |
Species | Human |
Gene Type | protein-coding |
Description | TELO2 interacting protein 2 |
Other Description | TELO2-interacting protein 2|Tel2 interacting protein 2 homolog |
Swissprots | Q96IM2 Q9H5N4 D3DSV7 Q6NXR4 |
Accessions | CAK32283 EAW63397 EAW63398 EAW63399 Q6NXR4 AI890434 AK026916 BAB15590 AK308918 AL530920 BC007387 AAH07387 BC066935 AAH66935 BX648410 DA617987 DB047280 DB112682 DB113350 JF432833 ADZ16050 XM_011544665 XP_011542967 NM_001102401 NP_001095871 NM_001265581 NP_001252510 NM_025115 NP_079391 |
Function | Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. {ECO:0000269|PubMed:20801936, ECO:0000269|PubMed:20810650}. |
C8orf41 fusion protein - ag15641 from Proteintech Group
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C8orf41 fusion protein - Ag14776 from Proteintech Group
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Recombinant Human TTI2 - TTI2-1225H from Creative Biomart
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Recombinant Human TELO2-interacting protein 2(TTI2) - CSB-YP764687HU CSB-EP764687HU CSB-BP764687HU CSB-MP764687HU from Cusabio
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TTI2 (transcript variant 2) - TP309782 from Acris Antibodies
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TELO2-interacting protein 2 (TTI2), Recombinant Protein - MBS1415677 from MyBioSource
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C8orf41/TTI2 Recombinant Protein Antigen - NBP1-82086PEP from Novus Biologicals
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C8orf41/TTI2 Recombinant Protein Antigen - NBP1-82085PEP from Novus Biologicals
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C8orf41-Blocking-Peptide-N-term - BP11947a from Abgent, a WuXi AppTec company
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TTI2 Peptide, Human - M34GP16821H from Creative Peptides
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