Gene Symbol | TTI2 |
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Entrez Gene | 80185 |
Alt Symbol | C8orf41, MRT39 |
Species | Human |
Gene Type | protein-coding |
Description | TELO2 interacting protein 2 |
Other Description | TELO2-interacting protein 2|Tel2 interacting protein 2 homolog |
Swissprots | Q96IM2 Q9H5N4 D3DSV7 Q6NXR4 |
Accessions | CAK32283 EAW63397 EAW63398 EAW63399 Q6NXR4 AI890434 AK026916 BAB15590 AK308918 AL530920 BC007387 AAH07387 BC066935 AAH66935 BX648410 DA617987 DB047280 DB112682 DB113350 JF432833 ADZ16050 XM_011544665 XP_011542967 NM_001102401 NP_001095871 NM_001265581 NP_001252510 NM_025115 NP_079391 |
Function | Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. {ECO:0000269|PubMed:20801936, ECO:0000269|PubMed:20810650}. |
TTI2 (S-12) - sc-87597 from Santa Cruz Biotechnology
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TTI2 (H-46) - sc-382066 from Santa Cruz Biotechnology
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TTI2 (Q-14) - sc-87596 from Santa Cruz Biotechnology
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Anti-C8ORF41 antibody - C-terminal - ab176698 from Abcam
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Anti-TTI2 / C8orf41 Antibody (aa458-508) - LS-C286167 from LifeSpan Bioscience
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C8orf41/TTI2 Antibody - NBP1-82085 from Novus Biologicals
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C8orf41/TTI2 Antibody - NBP1-82086 from Novus Biologicals
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C8orf41/TTI2 Antibody - NBP1-80571 from Novus Biologicals
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Anti-TTI2 antibody produced in rabbit - HPA029823 from Sigma-Aldrich
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Anti-TTI2 antibody produced in rabbit - HPA023523 from Sigma-Aldrich
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TTI2 Antibody - N-terminal region (ARP68059_P050) - ARP68059_P050 from Aviva Systems Biology
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TTI2 antibody - 20779-1-AP from Acris Antibodies
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TTI2 antibody - H00080185-B01P from Acris Antibodies
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C8orf41 antibody - 20779-1-AP from Proteintech Group
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TTI2 Antibody - A303-476A from Bethyl Labs
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Anti-TTI2 (aa 458-508) polyclonal antibody - DPABH-12055 from Creative Diagnostics
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TTI2 antibody - TA331723 from Acris Antibodies
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TTI2 antibody - orb326714 from Biorbyt
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C8orf41, Polyclonal Antibody - MBS767372 from MyBioSource
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anti-C8orf41 antibody - A001140 from Biobool
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Anti-TTI2 Antibody A12943 - A12943 from Boster Bio
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TTI2 Antibody - N-terminal region : Biotin (ARP68059_P050-Biotin) - ARP68059_P050-Biotin from Aviva Systems Biology
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TTI2 Antibody - N-terminal region : FITC (ARP68059_P050-FITC) - ARP68059_P050-FITC from Aviva Systems Biology
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TTI2 Antibody - N-terminal region : HRP (ARP68059_P050-HRP) - ARP68059_P050-HRP from Aviva Systems Biology
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C8ORF41 Antibody - middle region (ARP83682_P050) - ARP83682_P050 from Aviva Systems Biology
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