ZNF385A

Gene Symbol ZNF385A
Entrez Gene 25946
Alt Symbol HZF, RZF, ZFP385, ZNF385
Species Human
Gene Type protein-coding
Description zinc finger protein 385A
Other Description hematopoietic zinc finger protein|retinal zinc finger protein|zinc finger protein 385
Swissprots F1T0F1 J3KNS3 B2RDN5 Q5VH53 B4DKH2 Q9H7R6 Q96PM9 Q9UFU3
Accessions EAW96777 EAW96778 EAW96779 Q96PM9 AB593085 BAJ84025 AF304052 AAL08625 AK024404 BAB14910 AK092724 AK296564 BAG59184 AK315613 BAG37982 AL117462 CAB55938 AY461717 AAS19275 BC029752 AAH29752 BM476090 BM546460 BP305142 CR457327 CAG33608 DB116264 DB169664 XM_005268783 XP_005268840 XM_006719342 XP_006719405 XM_011538168 XP_011536470 XM_011538169 XP_011536471 XM_011538170 XP_011536472 XM_011538171 XP_011536473 NM_001130967 NP_001124439 NM_001130968 NP_001124440 NM_001290001 NP_001276930 NM_001290002 NP_001276931 NM_001290004 NP_001276933 NM_015481 NP_056296
Function RNA-binding protein that affects the localization and the translation of a subset of mRNA. May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA and regulation of its translation. Targets ITPR1 mRNA to dendrites in Purkinje cells, and may regulate its activity-dependent translation. With ELAVL1, binds the 3'-UTR of p53/TP53 mRNAs to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti- proliferative activity. May also bind CCNB1 mRNA. Alternatively, may also regulate p53/TP53 activity through direct protein-protein interaction. Interacts with p53/TP53 and promotes cell-cycle arrest over apoptosis enhancing preferentially the DNA binding and transactivation of p53/TP53 on cell-cycle arrest target genes over proapoptotic target genes. May also regulate the ubiquitination and stability of CDKN1A promoting DNA damage-induced cell cycle arrest. Also plays a role in megakaryocytes differentiation. {E
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15527981}. Nucleus, nucleolus {ECO:0000269|PubMed:15527981}. Cell projection, dendrite {ECO:0000250}. Note=Detected in dendrites of Purkinje cells and hippocampal neurons. {ECO:0000250}.
Tissue Specificity Expressed predominantly in the retina. {ECO:0000269|PubMed:15527981}.

ZNF385A CRISPR/Cas9 KO Plasmid (h) - sc-409249 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF385A HDR Plasmid (h) - sc-409249-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF385A Double Nickase Plasmid (h) - sc-409249-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF385A Double Nickase Plasmid (h2) - sc-409249-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF385A CRISPR Activation Plasmid (h) - sc-409249-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF385A CRISPR Activation Plasmid (h2) - sc-409249-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF385A Lentiviral Activation Particles (h) - sc-409249-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF385A Lentiviral Activation Particles (h2) - sc-409249-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF385A siRNA (h) - sc-95676 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZNF385A shRNA Plasmid (h) - sc-95676-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZNF385A shRNA (h) Lentiviral Particles - sc-95676-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU117041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23421 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23421 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ZNF385A siRNA (Human) - CRH8609 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZNF385 RNAi - H00025946-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ZNF385A - MBS8203406 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZNF385A (NM_015481.1) - SHH453804 from Creative biogene

Category siRNA
Species Reactivities Human

Human ZNF385A siRNA - orb269111 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZNF385A shRNA Plasmid (Human) - CHH8609 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ZNF385A miRNA 3'UTR clone - MiUTR1H-11584 from Creative biogene

Species Reactivities Human

ZNF385A miRNA 3'UTR clone - MiUTR3H-10423 from Creative biogene

Species Reactivities Human

ZNF385A miRNA 3'UTR clone - MiUTR3H-10424 from Creative biogene

Species Reactivities Human
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