Gene Symbol | FHOD1 |
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Entrez Gene | 29109 |
Alt Symbol | FHOS |
Species | Human |
Gene Type | protein-coding |
Description | formin homology 2 domain containing 1 |
Other Description | FH1/FH2 domain-containing protein 1|formin homolog overexpressed in spleen 1 |
Swissprots | Q9Y613 Q8N521 Q6Y1F2 Q76MS8 Q59F76 |
Accessions | EAW83109 EAW83110 EAW83111 EAW83112 EAW83113 Q9Y613 AA609867 AB041046 BAD06250 AB209584 BAD92821 AF113615 AAD39906 AK025992 AK301157 BAG62747 AK304232 BAG65101 AY192154 AAO38757 BC033084 AAH33084 CN302043 KJ658417 AID62088 XM_005255909 XP_005255966 XM_005255910 XP_005255967 XM_006721180 XP_006721243 XM_011523043 XP_011521345 XM_011523044 XP_011521346 XM_011523045 XP_011521347 XR_933285 XR_933286 NM_013241 NP_037373 |
Function | Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing. {ECO:0000269|PubMed:14576350, ECO:0000269|PubMed:15878344, ECO:0000269|PubMed:18694941}. |
Subcellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, bleb. Note=Predominantly cytoplasmic. |
Tissue Specificity | Ubiquitous. Highly expressed in spleen. |
FHOD1 (B-6) - sc-365433 from Santa Cruz Biotechnology
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FHOD1 (D-6) - sc-365437 from Santa Cruz Biotechnology
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FHOD1 (C-14) - sc-46964 from Santa Cruz Biotechnology
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FHOD1 (C-20) - sc-46965 from Santa Cruz Biotechnology
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FHOD1 (H-77) - sc-99209 from Santa Cruz Biotechnology
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Anti-FHOD1 (phospho T1141) antibody - ab157589 from Abcam
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Anti-FHOD1 antibody - ab73443 from Abcam
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Anti-FHOD1 antibody - ab129647 from Abcam
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Anti-FHOD1 antibody [5.3_1G6] - ab128009 from Abcam
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Anti-FHOS / FHOD1 Antibody (aa567-616) - LS-C201763 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa985-1013) - LS-C166153 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa1089-1106) - LS-C143851 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa1089-1106) - LS-C148949 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa348-365) - LS-C143852 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa348-365) - LS-C148954 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa985-1013, AP) - LS-C222552 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa985-1013, APC) - LS-C222553 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa985-1013, FITC) - LS-C222555 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa985-1013, Biotin) - LS-C222554 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa985-1013, Azide-free, HRP) - LS-C222556 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa985-1013, PE) - LS-C222557 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody (aa984-1013) - LS-C321389 from LifeSpan Bioscience
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Anti-FHOS / FHOD1 Antibody - LS-C307546 from LifeSpan Bioscience
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FMNL2 Antibody - NBP2-24748 from Novus Biologicals
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FHOD1 Antibody - NBP1-83900 from Novus Biologicals
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