Gene Symbol | FHOD1 |
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Entrez Gene | 29109 |
Alt Symbol | FHOS |
Species | Human |
Gene Type | protein-coding |
Description | formin homology 2 domain containing 1 |
Other Description | FH1/FH2 domain-containing protein 1|formin homolog overexpressed in spleen 1 |
Swissprots | Q9Y613 Q8N521 Q6Y1F2 Q76MS8 Q59F76 |
Accessions | EAW83109 EAW83110 EAW83111 EAW83112 EAW83113 Q9Y613 AA609867 AB041046 BAD06250 AB209584 BAD92821 AF113615 AAD39906 AK025992 AK301157 BAG62747 AK304232 BAG65101 AY192154 AAO38757 BC033084 AAH33084 CN302043 KJ658417 AID62088 XM_005255909 XP_005255966 XM_005255910 XP_005255967 XM_006721180 XP_006721243 XM_011523043 XP_011521345 XM_011523044 XP_011521346 XM_011523045 XP_011521347 XR_933285 XR_933286 NM_013241 NP_037373 |
Function | Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing. {ECO:0000269|PubMed:14576350, ECO:0000269|PubMed:15878344, ECO:0000269|PubMed:18694941}. |
Subcellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, bleb. Note=Predominantly cytoplasmic. |
Tissue Specificity | Ubiquitous. Highly expressed in spleen. |
Human FHOD1 protein fragment - ab162223 from Abcam
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FHOS / FHOD1 Antibody Blocking Peptide - LS-E4299 from LifeSpan Bioscience
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Recombinant Human FHOD1 Protein - H00029109-Q01 from Novus Biologicals
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FHOD1-Antibody-C-term-Blocking-Peptide - BP16586b from Abgent, a WuXi AppTec company
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FHOD1 - H00029109-Q01-10 from Acris Antibodies
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FHOD1 - H00029109-Q01-25 from Acris Antibodies
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Recombinant Human FH1/FH2 domain-containing protein 1(FHOD1) ,partial - CSB-YP896540HU CSB-EP896540HU CSB-BP896540HU CSB-MP896540HU from Cusabio
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FHOD1 - TP307683 from Acris Antibodies
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FHOD1 Recombinant Protein Antigen - NBP1-83900PEP from Novus Biologicals
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FHOD1 Peptide, Human - M34GP05738H from Creative Peptides
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FH1/FH2 domain-containing protein 1 (FHOD1), partial, Recombinant Protein - MBS1427696 from MyBioSource
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