AADAC

Gene Symbol AADAC
Entrez Gene 13
Alt Symbol CES5A1, DAC
Species Human
Gene Type protein-coding
Description arylacetamide deacetylase
Other Description arylacetamide deacetylase (esterase)
Swissprots P22760 Q8N1A9 D3DNJ6 A8K3L3
Accessions EAW78791 EAW78792 P22760 AK290628 BAF83317 AV705031 BC020706 BC032309 AAH32309 L32179 AAA35551 XM_005247104 XP_005247161 NM_001086 NP_001077
Function Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. {ECO:0000269|PubMed:17936933, ECO:0000269|PubMed:19339378, ECO:0000269|PubMed:22207054, ECO:0000269|PubMed:22415931, ECO:0000269|PubMed:23542347}.
Subcellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein.
Tissue Specificity Detected in liver (at protein level). Mainly expressed in liver, small intestine, colon, adrenal gland and bladder. {ECO:0000269|PubMed:19339378, ECO:0000269|PubMed:22207054, ECO:0000269|PubMed:22415931}.

AADAC CRISPR/Cas9 KO Plasmid (h) - sc-410533 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AADAC HDR Plasmid (h) - sc-410533-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AADAC Double Nickase Plasmid (h) - sc-410533-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AADAC Double Nickase Plasmid (h2) - sc-410533-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AADAC CRISPR Activation Plasmid (h) - sc-410533-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AADAC CRISPR Activation Plasmid (h2) - sc-410533-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AADAC Lentiviral Activation Particles (h) - sc-410533-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AADAC Lentiviral Activation Particles (h2) - sc-410533-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AADAC siRNA (h) - sc-77919 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AADAC shRNA Plasmid (h) - sc-77919-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AADAC shRNA (h) Lentiviral Particles - sc-77919-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU027081 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2602 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2602 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03058 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03058

AADAC siRNA (Human) - CRH0006 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AADAC RNAi - H00000013-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

AADAC - MBS8220381 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AADAC (NM_001086.2) - SHH228534 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AADAC(NM_001086.2) - SHG021833 from Creative biogene

Category siRNA
Species Reactivities Human

Human AADAC siRNA - orb260508 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AADAC shRNA Plasmid (Human) - CHH0006 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AADAC miRNA 3'UTR clone - MiUTR1H-00007 from Creative biogene

Species Reactivities Human
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