Gene Symbol | ESYT1 |
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Entrez Gene | 23344 |
Alt Symbol | FAM62A, MBC2 |
Species | Human |
Gene Type | protein-coding |
Description | extended synaptotagmin-like protein 1 |
Other Description | extended synaptotagmin-1|family with sequence similarity 62 (C2 domain containing), member A|membrane-bound C2 domain-containing protein |
Swissprots | Q9BSJ8 A0FGR7 Q9Y416 Q9H6W2 A8K2S2 O94848 Q6PJN4 Q9H6J1 |
Accessions | EAW96890 EAW96891 EAW96892 EAW96893 Q9BSJ8 AB018290 BAA34467 AJ346011 AK022790 BAG51117 AK025463 BAB15139 AK025878 BAB15268 AK074368 AK128730 BAG54718 AK225035 AK290337 BAF83026 AL050134 CAB43284 BC004998 AAH04998 BC013880 DB100366 DQ993200 ABJ97705 EU832620 ACE87711 EU832692 ACE87024 NM_001184796 NP_001171725 NM_015292 NP_056107 |
Function | Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. {ECO:0000250, ECO:0000269|PubMed:23791178, ECO:0000269|PubMed:24183667}. |
Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Peripheral membrane protein. Note=Localizes primarily to the endoplasmic reticulum. Recruited to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:17360437}. |
FAM62A (P-15) - sc-167812 from Santa Cruz Biotechnology
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FAM62A (T-14) - sc-167813 from Santa Cruz Biotechnology
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Anti-FAM62A antibody - ab118805 from Abcam
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Anti-FAM62A antibody - ab167270 from Abcam
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Anti-FAM62A antibody - ab130630 from Abcam
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Anti-FAM62A antibody - C-terminal - ab189007 from Abcam
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Anti-ESYT1 Antibody (aa1038-1050) IHC-plus⢠- LS-B8299 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (Internal) IHC-plus⢠- LS-A9547 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (Internal) IHC-plus⢠- LS-A9546 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (C-Terminus) IHC-plus⢠- LS-A9554 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (Internal) IHC-plus⢠- LS-A9549 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (aa1002-1031, AP) - LS-C208897 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (aa1002-1031, APC) - LS-C208898 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (aa1002-1031, Biotin) - LS-C208899 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (aa1002-1031) - LS-C167836 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (aa1002-1031, Azide-free, HRP) - LS-C208901 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (aa1002-1031, FITC) - LS-C208900 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (aa1002-1031, PE) - LS-C208902 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (aa1054-1104) - LS-C286236 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (aa350-400) - LS-C290044 from LifeSpan Bioscience
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Anti-ESYT1 Antibody - LS-C307468 from LifeSpan Bioscience
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Anti-ESYT1 Antibody (aa1001-1031) - LS-C321207 from LifeSpan Bioscience
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FAM62A Antibody - NBP1-84741 from Novus Biologicals
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FAM62A Antibody - NBP1-00184 from Novus Biologicals
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FAM62A Antibody - NBP1-78751 from Novus Biologicals
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