ESYT1

Gene Symbol ESYT1
Entrez Gene 23344
Alt Symbol FAM62A, MBC2
Species Human
Gene Type protein-coding
Description extended synaptotagmin-like protein 1
Other Description extended synaptotagmin-1|family with sequence similarity 62 (C2 domain containing), member A|membrane-bound C2 domain-containing protein
Swissprots Q9BSJ8 A0FGR7 Q9Y416 Q9H6W2 A8K2S2 O94848 Q6PJN4 Q9H6J1
Accessions EAW96890 EAW96891 EAW96892 EAW96893 Q9BSJ8 AB018290 BAA34467 AJ346011 AK022790 BAG51117 AK025463 BAB15139 AK025878 BAB15268 AK074368 AK128730 BAG54718 AK225035 AK290337 BAF83026 AL050134 CAB43284 BC004998 AAH04998 BC013880 DB100366 DQ993200 ABJ97705 EU832620 ACE87711 EU832692 ACE87024 NM_001184796 NP_001171725 NM_015292 NP_056107
Function Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. {ECO:0000250, ECO:0000269|PubMed:23791178, ECO:0000269|PubMed:24183667}.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Peripheral membrane protein. Note=Localizes primarily to the endoplasmic reticulum. Recruited to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:17360437}.

Human ESYT1 ORF clone (NM_001184796.1) - CDCR061514 from Creative biogene

Species Human

Human ESYT1 ORF Clone (BC013880) - CDCS418518 from Creative biogene

Species Human
Accession Q9BSJ8

Human ESYT1 cDNA Clone(NM_001184796.1) - CDFH006131 from Creative biogene

Species Human
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