AP4M1

Gene Symbol	AP4M1
Entrez Gene	9179
Alt Symbol	CPSQ3, MU-4, MU-ARP2, SPG50
Species	Human
Gene Type	protein-coding
Description	adaptor-related protein complex 4, mu 1 subunit
Other Description	AP-4 adaptor complex mu subunit\|AP-4 complex subunit mu-1\|adapter-related protein complex 4 mu-1 subunit\|adapter-related protein complex 4 subunit mu-1\|adaptor-related protein complex 4 subunit mu-1\|adaptor-related protein complex AP-4 mu4 subunit\|mu subunit of AP-4\|mu-adaptin-related protein 2\|mu-adaptin-related protein-2\|mu4\|mu4-adaptin
Swissprots	O00189 D6W5U1 Q9UHK9 Q8WV65
Accessions	EAL23854 EAW76594 EAW76595 EAW76596 EAW76597 O00189 AF020796 AAD25869 AF155158 AAD43328 AK055686 AK293590 BAG57057 AK296651 BAG59249 AK304489 BAG65298 AK315782 BC012023 BC018705 AAH18705 BX640759 CAE45865 DC413622 HQ447727 ADQ32212 Y08387 CAA69667 XM_005250689 XP_005250746 XM_005250690 XP_005250747 XM_006716175 XP_006716238 XM_011516685 XP_011514987 XM_011516686 XP_011514988 XM_011516687 XP_011514989 NM_004722 NP_004713
Function	Component of the AP-4 complex, a novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal- lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network (TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP. {ECO:0000269\|PubMed:11139587, ECO:0000269\|PubMed:20230749}.
Subcellular Location	Golgi apparatus, trans-Golgi network. Membrane, coated pit. Note=Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells.
Tissue Specificity	Ubiquitous. Highly expressed in testis and lowly expressed in brain and lung. {ECO:0000269\|PubMed:10436028, ECO:0000269\|PubMed:9013859}.
Top Pathways	Lysosome

AP-4μ (G-20) - sc-18488 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

AP-4μ (ZB-18) - sc-101258 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

AP-4μ (ZB-18): sc-101258. Western blot analysis of AP-4μ expression in HeLa whole cell lysate.

Anti-AP4M1 antibody - ab96306 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 antibody (ab96306) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-AP4M1 antibody - ab196255 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 antibody (ab196255) at 1/1000 dilution + A431 cell lysate

Anti-AP4M1 antibody - ab173134 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 antibody (ab173134) at 1/100 dilution + CEM cell line lysate at 35 µg

Anti-AP4M1 antibody - ab56473 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-AP4M1 antibody - ab172231 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-AP4M1 antibody (ab172231) at 1 µg/mlLane 1 : AP4M1 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateSecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-AP4M1 antibody - C-terminal - ab136691 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 antibody - C-terminal (ab136691) at 1 µg/ml + 293T cell lysate at 10 µg

Anti-AP4M1 Antibody (aa354-454, clone 10B186, Azide-free) - LS-C183485 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal
Clone	10B186

Anti-AP4M1 Antibody (aa223-251, Biotin) - LS-C232728 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 Antibody (aa223-251, APC) - LS-C232726 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 Antibody (aa223-251, AP) - LS-C232729 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 Antibody (aa223-251, FITC) - LS-C232730 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 Antibody (aa223-251, PE) - LS-C232733 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 Antibody (aa345-394) - LS-C169942 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 Antibody (aa223-251) - LS-C159084 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

AP4M1 Antibody western blot of CEM cell line lysates (35 ug/lane). The AP4M1 antibody detected the AP4M1 protein (arrow).

Anti-AP4M1 Antibody (aa223-251, Azide-free, HRP) - LS-C249437 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 Antibody - LS-C309464 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 Antibody - LS-C306280 from LifeSpan Bioscience

Prices	$455.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-AP4M1 Antibody (aa222-251) - LS-C319520 from LifeSpan Bioscience

Prices	$435.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-AP4M1 Antibody (aa354-454) - LS-C306281 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-AP4M1 Antibody (aa70-295) - LS-C186399 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

IHC of paraffin-embedded TOV-21G xenograft using AP4M1 antibody at 1:500 dilution.

AP4M1 Antibody - NBP2-14874 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: AP4M1 Antibody [NBP2-14874] - Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE; antibody diluted at 1:10000.

AP4M1 Antibody - H00009179-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

AP4M1 Antibody (2C4) - H00009179-M01 from Novus Biologicals

Prices	$349.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2C4

Western Blot: AP4M1 Antibody (2C4) [H00009179-M01] - AP4M1 monoclonal antibody (M01), clone 2C4 Western Blot analysis of AP4M1 expression in HeLa ( Cat # L013V1 ).

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