AP4M1

Gene Symbol	AP4M1
Entrez Gene	9179
Alt Symbol	CPSQ3, MU-4, MU-ARP2, SPG50
Species	Human
Gene Type	protein-coding
Description	adaptor-related protein complex 4, mu 1 subunit
Other Description	AP-4 adaptor complex mu subunit|AP-4 complex subunit mu-1|adapter-related protein complex 4 mu-1 subunit|adapter-related protein complex 4 subunit mu-1|adaptor-related protein complex 4 subunit mu-1|adaptor-related protein complex AP-4 mu4 subunit|mu subunit of AP-4|mu-adaptin-related protein 2|mu-adaptin-related protein-2|mu4|mu4-adaptin
Swissprots	O00189 D6W5U1 Q9UHK9 Q8WV65
Accessions	EAL23854 EAW76594 EAW76595 EAW76596 EAW76597 O00189 AF020796 AAD25869 AF155158 AAD43328 AK055686 AK293590 BAG57057 AK296651 BAG59249 AK304489 BAG65298 AK315782 BC012023 BC018705 AAH18705 BX640759 CAE45865 DC413622 HQ447727 ADQ32212 Y08387 CAA69667 XM_005250689 XP_005250746 XM_005250690 XP_005250747 XM_006716175 XP_006716238 XM_011516685 XP_011514987 XM_011516686 XP_011514988 XM_011516687 XP_011514989 NM_004722 NP_004713
Function	Component of the AP-4 complex, a novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal- lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network (TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP. {ECO:0000269|PubMed:11139587, ECO:0000269|PubMed:20230749}.
Subcellular Location	Golgi apparatus, trans-Golgi network. Membrane, coated pit. Note=Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells.
Tissue Specificity	Ubiquitous. Highly expressed in testis and lowly expressed in brain and lung. {ECO:0000269|PubMed:10436028, ECO:0000269|PubMed:9013859}.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AP4M1 full length protein - ab132604 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human AP4M1 protein fragment - ab127152 from Abcam Category Protein Prices $364.00 Sizes 50 µg Source E. coli Species Human

AP4M1 Antibody Blocking Peptide - LS-E5038 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AP4M1 Antibody Blocking Peptide - LS-E24400 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AP4M1 Partial Recombinant Protein - H00009179-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human AP4M1 Protein - H00009179-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

AP4M1-Antibody-Center-Blocking-Peptide - BP17446c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AP4 complex subunit mu-1 - H00009179-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

AP4 complex subunit mu-1 - H00009179-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

AP4 complex subunit mu-1 - H00009179-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

AP4 complex subunit mu-1 - H00009179-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

AP4M1 fusion protein - ag2222 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human AP4M1, His-tagged - AP4M1-3544H from Creative Biomart Category Protein Source E. Coli or Yeast Species Human

Recombinant Human AP-4 complex subunit mu-1(AP4M1) - CSB-YP001883HU CSB-EP001883HU CSB-BP001883HU CSB-MP001883HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

AP-4 complex subunit mu-1 (AP4M1) , Recombinant Protein - MBS1143456 from MyBioSource Category Protein Prices $2,005.00, $2,005.00, $2,470.00, $2,470.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

AP4M1 Peptide, Human - M34GP00731H from Creative Peptides Category Peptide Source Synthetic. Species Human

AP4M1 Recombinant Protein Antigen - NBP2-56456PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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