FXYD1

Gene Symbol FXYD1
Entrez Gene 5348
Alt Symbol PLM
Species Human
Gene Type protein-coding
Description FXYD domain containing ion transport regulator 1
Other Description phospholemman
Swissprots O00168 A8K196
Accessions CAM55994 O00168 AA524547 AK289811 BAF82500 BC032800 AAH32800 BM691130 BM856555 BX115036 EU176238 ABW03689 EU176531 ABW03332 GQ258667 ACT90639 H57207 HY107209 HY111815 HY151101 HY151827 R46545 R72515 U72245 AAC51286 NM_001278717 NP_001265646 NM_001278718 NP_001265647 NM_005031 NP_005022 NM_021902 NP_068702
Function May have a functional role in muscle contraction. Induces a hyperpolarization-activated chloride current when exogenously expressed.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Highest expression in skeletal muscle and heart. Moderate levels in brain, placenta, lung, liver, pancreas, uterus, bladder, prostate, small intestine and colon with mucosal lining. Very low levels in kidney, colon and small intestine without mucosa, prostate without endothelial lining, spleen, and testis.
Top Pathways cAMP signaling pathway

FXYD1-Over-expression-Lysate - LY13137a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag FXYD1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FXYD1 gene

FXYD1 overexpression lysate - LY402884 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

FXYD1 overexpression lysate - LY417593 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

FXYD1 293 Cell Lysate - 408234 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

FXYD1 293 Cell Lysate - 402510 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Phospholemman Overexpression Lysate (Native) - NBL1-10875 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Phospholemman Overexpression Lysate (Adult Normal) [NBL1-10875] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Phospholemman.

Phospholemman Overexpression Lysate (Native) - NBL1-10876 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Phospholemman Overexpression Lysate (Adult Normal) [NBL1-10876] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Phospholemman.

FXYD1 Over-expression Lysate Product - GWB-ED5262 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

FXYD1 Over-expression Lysate Product - GWB-CD5D88 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Panoply™ Human FXYD1 Knockdown Stable Cell Line - CSC-DC005973 from Creative biogene

Category Cell Line
Species Human
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