Gene Symbol | FXYD1 |
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Entrez Gene | 5348 |
Alt Symbol | PLM |
Species | Human |
Gene Type | protein-coding |
Description | FXYD domain containing ion transport regulator 1 |
Other Description | phospholemman |
Swissprots | O00168 A8K196 |
Accessions | CAM55994 O00168 AA524547 AK289811 BAF82500 BC032800 AAH32800 BM691130 BM856555 BX115036 EU176238 ABW03689 EU176531 ABW03332 GQ258667 ACT90639 H57207 HY107209 HY111815 HY151101 HY151827 R46545 R72515 U72245 AAC51286 NM_001278717 NP_001265646 NM_001278718 NP_001265647 NM_005031 NP_005022 NM_021902 NP_068702 |
Function | May have a functional role in muscle contraction. Induces a hyperpolarization-activated chloride current when exogenously expressed. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Highest expression in skeletal muscle and heart. Moderate levels in brain, placenta, lung, liver, pancreas, uterus, bladder, prostate, small intestine and colon with mucosal lining. Very low levels in kidney, colon and small intestine without mucosa, prostate without endothelial lining, spleen, and testis. |
Top Pathways | cAMP signaling pathway |
Human FXYD1 peptide - ab88161 from Abcam
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FXYD1 / Phospholemman Antibody Blocking Peptide - LS-E16955 from LifeSpan Bioscience
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FXYD1 / Phospholemman Antibody Blocking Peptide - LS-E7331 from LifeSpan Bioscience
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FXYD1 Blocking Peptide - 33R-1515 from Fitzgerald
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FXYD1 fusion protein - Ag4669 from Proteintech Group
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Recombinant Human FXYD1, GST-tagged - FXYD1-13054H from Creative Biomart
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Recombinant Human Phospholemman(FXYD1) - CSB-YP009089HU CSB-EP009089HU CSB-BP009089HU CSB-MP009089HU from Cusabio
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Phospholemman (transcript variant a) - TP307475 from Acris Antibodies
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Phospholemman (FXYD1), Recombinant Protein - MBS1066547 from MyBioSource
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Phospholemman Protein - NBP1-87263PEP from Novus Biologicals
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FXYD1-Blocking-Peptide-C-term - BP20771c from Abgent, a WuXi AppTec company
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FXYD1 Peptide, Human - M34GP05973H from Creative Peptides
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Phospholemman, Recombinant Protein - MBS7042771 from MyBioSource
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FXYD1 fusion protein - Ag25307 from Proteintech Group
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