FXYD1

Gene Symbol FXYD1
Entrez Gene 5348
Alt Symbol PLM
Species Human
Gene Type protein-coding
Description FXYD domain containing ion transport regulator 1
Other Description phospholemman
Swissprots O00168 A8K196
Accessions CAM55994 O00168 AA524547 AK289811 BAF82500 BC032800 AAH32800 BM691130 BM856555 BX115036 EU176238 ABW03689 EU176531 ABW03332 GQ258667 ACT90639 H57207 HY107209 HY111815 HY151101 HY151827 R46545 R72515 U72245 AAC51286 NM_001278717 NP_001265646 NM_001278718 NP_001265647 NM_005031 NP_005022 NM_021902 NP_068702
Function May have a functional role in muscle contraction. Induces a hyperpolarization-activated chloride current when exogenously expressed.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Highest expression in skeletal muscle and heart. Moderate levels in brain, placenta, lung, liver, pancreas, uterus, bladder, prostate, small intestine and colon with mucosal lining. Very low levels in kidney, colon and small intestine without mucosa, prostate without endothelial lining, spleen, and testis.
Top Pathways cAMP signaling pathway

Human FXYD1 peptide - ab88161 from Abcam

Category Peptide

FXYD1 / Phospholemman Antibody Blocking Peptide - LS-E16955 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FXYD1 / Phospholemman Antibody Blocking Peptide - LS-E7331 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FXYD1 Blocking Peptide - 33R-1515 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

FXYD1 fusion protein - Ag4669 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human FXYD1, GST-tagged - FXYD1-13054H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Phospholemman(FXYD1) - CSB-YP009089HU CSB-EP009089HU CSB-BP009089HU CSB-MP009089HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Phospholemman (transcript variant a) - TP307475 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
Phospholemman

Phospholemman (FXYD1), Recombinant Protein - MBS1066547 from MyBioSource

Category Protein
Prices $1,375.00, $1,835.00
Sizes 1 mg (E-Coli), 1 mg (Yeast)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Phospholemman Protein - NBP1-87263PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

FXYD1-Blocking-Peptide-C-term - BP20771c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

FXYD1 Peptide, Human - M34GP05973H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Phospholemman, Recombinant Protein - MBS7042771 from MyBioSource

Category Protein
Prices $925.00, $1,905.00, $3,115.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Human

FXYD1 fusion protein - Ag25307 from Proteintech Group

Category Protein
Source E. coli -derived, PET28a
Species Human
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