FXYD1

Gene Symbol FXYD1
Entrez Gene 5348
Alt Symbol PLM
Species Human
Gene Type protein-coding
Description FXYD domain containing ion transport regulator 1
Other Description phospholemman
Swissprots O00168 A8K196
Accessions CAM55994 O00168 AA524547 AK289811 BAF82500 BC032800 AAH32800 BM691130 BM856555 BX115036 EU176238 ABW03689 EU176531 ABW03332 GQ258667 ACT90639 H57207 HY107209 HY111815 HY151101 HY151827 R46545 R72515 U72245 AAC51286 NM_001278717 NP_001265646 NM_001278718 NP_001265647 NM_005031 NP_005022 NM_021902 NP_068702
Function May have a functional role in muscle contraction. Induces a hyperpolarization-activated chloride current when exogenously expressed.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Highest expression in skeletal muscle and heart. Moderate levels in brain, placenta, lung, liver, pancreas, uterus, bladder, prostate, small intestine and colon with mucosal lining. Very low levels in kidney, colon and small intestine without mucosa, prostate without endothelial lining, spleen, and testis.
Top Pathways cAMP signaling pathway

phospholemman (A-8) - sc-390822 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
phospholemman (A-8): sc-390822. Western blot analysis of phospholemman expression in human heart (A) and human skeletal muscle (B) tissue extracts.

phospholemman (C-1) - sc-393415 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
phospholemman (C-1): sc-393415. Western blot analysis of phospholemman expression in human heart (A) and human skeletal muscle (B) tissue extracts.

phospholemman (H-40) - sc-367396 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

phospholemman (K-14) - sc-27966 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

phospholemman (M-40) - sc-367718 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
phospholemman (M-40): sc-367718. Western blot analysis of phospholemman expression in mouse heart tissue extract.

Anti-FXYD1 [EPR16081] antibody - ab191397 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16081
All lanes : Anti-FXYD1 [EPR16081] antibody (ab191397) at 1/10000 dilutionLane 1 : Human skeletal muscle lysateLane 2 : Human fetal heart lysateLane 3 : Human fetal liver lysateLysates/proteins at 20 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-FXYD1 antibody [EPR16082] - ab200204 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16082
Anti-FXYD1 antibody [EPR16082] (ab200204) at 1/1000 dilution + Human skeletal muscle lysate at 20 µgSecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-FXYD1 / Phospholemman Antibody - LS-C129184 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-FXYD1 / Phospholemman Antibody (Ser68, AP) - LS-C277441 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-FXYD1 / Phospholemman Antibody (Ser68, APC) - LS-C277442 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-FXYD1 / Phospholemman Antibody (Ser68, Biotin) - LS-C277443 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-FXYD1 / Phospholemman Antibody (Ser68, FITC) - LS-C277444 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-FXYD1 / Phospholemman Antibody (Ser68, Azide-free, HRP) - LS-C277445 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-FXYD1 / Phospholemman Antibody (Ser88, AP) - LS-C277446 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FXYD1 / Phospholemman Antibody (Ser88, APC) - LS-C277447 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FXYD1 / Phospholemman Antibody (Ser88, FITC) - LS-C277449 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FXYD1 / Phospholemman Antibody (Ser88, Biotin) - LS-C277448 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FXYD1 / Phospholemman Antibody (Ser68, PE) - LS-C277451 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-FXYD1 / Phospholemman Antibody (Ser88, Azide-free, HRP) - LS-C277450 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FXYD1 / Phospholemman Antibody (Ser88, PE) - LS-C277452 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FXYD1 / Phospholemman Antibody (N-Terminus) - LS-C111106 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
FXYD1 antibody LS-C111106 Western blot of Transfected 293T cell lysate.

Anti-FXYD1 / Phospholemman Antibody (phospho-Ser68, clone 41AT858.235) - LS-C96440 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
Clone 41AT858.235
Western blot of anti-PLM antibody in 293 cells transfected with a plasmid encoding PLM.

Anti-FXYD1 / Phospholemman Antibody (phospho-Ser68) - LS-C330442 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FXYD1 / Phospholemman Antibody (phospho-Ser88) - LS-C96998 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
The anti-Mouse Phospho-PLM-pS88 antibody is used for detection in mouse heart tissue lysate. Mouse Phospho-PLM-pS88 (arrow) was detected using the purified antibody.

Anti-FXYD1 / Phospholemman Antibody (aa69-101) - LS-C344627 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from rat brain tissue lysate with FXYD1 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.
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