Gene Symbol | OASL |
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Entrez Gene | 8638 |
Alt Symbol | OASLd, TRIP-14, TRIP14, p59 OASL, p59-OASL, p59OASL |
Species | Human |
Gene Type | protein-coding |
Description | 2'-5'-oligoadenylate synthetase-like |
Other Description | 2'-5'-OAS-RP|2'-5'-OAS-related protein|2'-5'-oligoadenylate synthase-like protein|59 kDa 2'-5'-oligoadenylate synthase-like protein|59 kDa 2'-5'-oligoadenylate synthetase-like protein|TR-interacting protein 14|thyroid receptor-interacting protein 14 |
Swissprots | Q9Y6K6 O75686 I1YDD2 B2RAZ2 Q17R95 Q9Y6K7 Q15646 |
Accessions | AAC41733 EAW98235 EAW98236 EAW98237 EAW98238 Q15646 AJ225089 CAA12396 AK023956 BAG51241 AK314419 BAG37039 AL711263 AW069118 BC117408 AAI17409 BC117410 AAI17411 BG339739 BG744291 BM909951 BM918192 DB005346 HQ258301 ADR83055 JQ792168 AFJ00074 NM_001261825 NP_001248754 NM_003733 NP_003724 NM_198213 NP_937856 |
Function | Does not have 2'-5'-OAS activity, but can bind double- stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L. {ECO:0000269|PubMed:18931074, ECO:0000269|PubMed:20074559, ECO:0000269|PubMed:9826176}. |
Subcellular Location | Isoform p56: Nucleus, nucleolus. Cytoplasm. |
Tissue Specificity | Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis. |
Human OASL protein fragment - ab160131 from Abcam
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OASL Antibody Blocking Peptide - LS-E8141 from LifeSpan Bioscience
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Recombinant Human OASL Protein - H00008638-Q01 from Novus Biologicals
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OASL Peptide - P1838 from Novus Biologicals
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OASL-Antibody-C-term-Blocking-Peptide - BP6230a from Abgent, a WuXi AppTec company
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OASL Blocking Peptide - 33R-1866 from Fitzgerald
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OASL Blocking Peptide - 33R-7944 from Fitzgerald
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OAS / TRIP14 - H00008638-Q01-10 from Acris Antibodies
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OAS / TRIP14 - H00008638-Q01-25 from Acris Antibodies
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OASL Peptide - 7775P from ProSci
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Recombinant 2',5'-Oligoadenylate Synthetase Like Protein (OASL) - RPF691Hu01 from Uscn Life Science Inc.
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Recombinant 2',5'-Oligoadenylate Synthetase Like Protein (OASL) - RPF691Hu01 from Cloud-clone
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Recombinant Human 59 kDa 2'-5'-oligoadenylate synthase-like protein(OASL) - CSB-YP614897HU CSB-EP614897HU CSB-BP614897HU CSB-MP614897HU from Cusabio
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OASL Protein - abx163690 from Abbexa
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OAS / TRIP14 (full length, N-term HIS tag, transcript variant 1) - TP760966 from Acris Antibodies
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OASL Recombinant Protein Antigen - NBP1-87363PEP from Novus Biologicals
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OASL Peptide, Human - M34GP10786H from Creative Peptides
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Human OASL protein (C-His) - orb311632 from Biorbyt
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OASL Recombinant Protein (OPCD05876) - OPCD05876 from Aviva Systems Biology
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OASL Recombinant Protein - 92-291 from ProSci
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OASL, Recombinant Protein - MBS8249527 from MyBioSource
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Recombinant Human OASL Protein, His-tagged - OASL-310H from Creative Biomart
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Recombinant Human OASL Protein, His-tagged - OASL-521H from Creative Biomart
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