Gene Symbol | HS6ST1 |
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Entrez Gene | 9394 |
Alt Symbol | HH15, HS6ST |
Species | Human |
Gene Type | protein-coding |
Description | heparan sulfate 6-O-sulfotransferase 1 |
Other Description | HS6ST-1|heparan-sulfate 6-O-sulfotransferase 1|heparan-sulfate 6-sulfotransferase |
Swissprots | O60243 B4DJ29 B4DEP2 Q9BVI1 Q53SL2 |
Accessions | AAY14736 EAW95357 EAW95358 EAW95359 O60243 AB006179 BAA25760 AK058121 AK293724 BAG57153 AK295898 BAG58691 AK304326 BAG65175 AL831893 BC001196 AAH01196 BC019025 BC047087 BC063521 BC096239 AAH96239 BC096240 AAH96240 BC099638 AAH99638 BC099639 AAH99639 BP219645 CV569969 DR005030 NM_004807 NP_004798 |
Function | 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid. {ECO:0000269|PubMed:21700882}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in fetal brain. {ECO:0000269|PubMed:9535912}. |
Top Pathways | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
HS6ST1 (Y-16) - sc-109943 from Santa Cruz Biotechnology
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HS6ST1 (C-9) - sc-398231 from Santa Cruz Biotechnology
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HS6ST1 (C-14) - sc-109941 from Santa Cruz Biotechnology
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Anti-HS6ST1 antibody - ab88488 from Abcam
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Anti-HS6ST1 antibody - ab69682 from Abcam
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Anti-HS6ST1 antibody - ab106195 from Abcam
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Anti-HS6ST1 Antibody - LS-C121962 from LifeSpan Bioscience
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Anti-HS6ST1 Antibody - LS-C143902 from LifeSpan Bioscience
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Anti-HS6ST1 Antibody (Internal) - LS-C144983 from LifeSpan Bioscience
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Anti-HS6ST1 Antibody (aa285-334) - LS-C151847 from LifeSpan Bioscience
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Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1 Antibody - AF5057 from Novus Biologicals
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Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1 Antibody - NBP1-92010 from Novus Biologicals
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Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1 Antibody (584308) [Unconjugated] - MAB5057 from Novus Biologicals
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Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1 Antibody - NBP1-21308 from Novus Biologicals
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Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1 Antibody (1G4) - H00009394-M01 from Novus Biologicals
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Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1 Antibody (1H4) - H00009394-M05A from Novus Biologicals
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Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1 Antibody - H00009394-A01 from Novus Biologicals
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HS6ST1 Polyclonal Antibody - bs-11854R from Bioss
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Rabbit Anti-HS6ST1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11854R-A350 from Bioss
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Rabbit Anti-HS6ST1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11854R-A488 from Bioss
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Rabbit Anti-HS6ST1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11854R-A555 from Bioss
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Rabbit Anti-HS6ST1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11854R-A647 from Bioss
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Rabbit Anti-HS6ST1 Polyclonal Antibody, Cy3 Conjugated - bs-11854R-Cy3 from Bioss
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Rabbit Anti-HS6ST1 Polyclonal Antibody, Cy5 Conjugated - bs-11854R-Cy5 from Bioss
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Rabbit Anti-HS6ST1 Polyclonal Antibody, Cy5.5 Conjugated - bs-11854R-Cy5.5 from Bioss
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