Gene Symbol | HS6ST1 |
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Entrez Gene | 9394 |
Alt Symbol | HH15, HS6ST |
Species | Human |
Gene Type | protein-coding |
Description | heparan sulfate 6-O-sulfotransferase 1 |
Other Description | HS6ST-1|heparan-sulfate 6-O-sulfotransferase 1|heparan-sulfate 6-sulfotransferase |
Swissprots | O60243 B4DJ29 B4DEP2 Q9BVI1 Q53SL2 |
Accessions | AAY14736 EAW95357 EAW95358 EAW95359 O60243 AB006179 BAA25760 AK058121 AK293724 BAG57153 AK295898 BAG58691 AK304326 BAG65175 AL831893 BC001196 AAH01196 BC019025 BC047087 BC063521 BC096239 AAH96239 BC096240 AAH96240 BC099638 AAH99638 BC099639 AAH99639 BP219645 CV569969 DR005030 NM_004807 NP_004798 |
Function | 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid. {ECO:0000269|PubMed:21700882}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in fetal brain. {ECO:0000269|PubMed:9535912}. |
Top Pathways | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
Human HS6ST1 peptide - ab69681 from Abcam
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Human HS6ST1 protein fragment - ab160468 from Abcam
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HS6ST1 Antibody Blocking Peptide - LS-E23659 from LifeSpan Bioscience
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Recombinant Human Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1 Protein - H00009394-Q01 from Novus Biologicals
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HS6ST1-Antibody-C-term-Blocking-Peptide - BP4929b from Abgent, a WuXi AppTec company
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Recombinant Human Heparan Sulfate-6-O-Sulfotransferase-1, CF - 5057-ST-020 from R&D Systems
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HS6ST1 - H00009394-Q01-10 from Acris Antibodies
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HS6ST1 - H00009394-Q01-25 from Acris Antibodies
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HS6ST1 fusion protein - Ag16242 from Proteintech Group
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Recombinant Human HS6ST1, GST-tagged - HS6ST1-13947H from Creative Biomart
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Recombinant Human HS6ST1, His-tagged - HS6ST1-420H from Creative Biomart
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Recombinant Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) - RPH878Hu01 from Uscn Life Science Inc.
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Recombinant Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) - RPH878Hu01 from Cloud-clone
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Recombinant Human Heparan-sulfate 6-O-sulfotransferase 1(HS6ST1) - CSB-YP010756HU CSB-EP010756HU CSB-BP010756HU CSB-MP010756HU from Cusabio
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Recombinant Human Heparan Sulfate-6-O-Sulfotransferase-1, CF - 5057-ST from R&D Systems
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Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1 Protein - NBP1-92010PEP from Novus Biologicals
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HS6ST1 Peptide, Human - M34GP07265H from Creative Peptides
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Heparan-sulfate 6-O-sulfotransferase 1, Recombinant Protein - MBS7042857 from MyBioSource
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Heparan-sulfate 6-O-sulfotransferase 1 (HS6ST1), Recombinant Protein - MBS1255915 from MyBioSource
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Recombinant Human Heparan Sulfate-6-O-Sulfotransferase-1, CF - 5057-ST from Novus Biologicals
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