Gene Symbol | NGB |
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Entrez Gene | 58157 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | neuroglobin |
Other Description | - |
Swissprots | Q9NPG2 |
Accessions | AAF62557 AAF63183 AAL98923 AAY16983 CAC12994 EAW81274 EAW81275 Q9NPG2 AF422797 AAL98924 AJ245946 CAC11133 AK098350 AK315395 BAG37788 BC032509 AAH32509 DQ890861 ABM81787 DQ894016 ABM84942 NM_021257 NP_067080 |
Function | Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. {ECO:0000269|PubMed:11029004, ECO:0000269|PubMed:11473128, ECO:0000269|PubMed:18416560, ECO:0000269|PubMed:21190290, ECO:0000269|PubMed:21296891}. |
Subcellular Location | Perikaryon {ECO:0000250}. Cytoplasm. Mitochondrion. |
Tissue Specificity | Predominantly expressed in brain, the strongest expression is seen in the frontal lobe, the subthalamic nucleus and the thalamus. {ECO:0000269|PubMed:11029004}. |
Human Neuroglobin full length protein - ab63278 from Abcam
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NGB Protein (OPPA00709) - OPPA00709 from Aviva Systems Biology
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Human NGB protein - orb244403 from Biorbyt
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Neuroglobin - H00058157-P01-10 from Acris Antibodies
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Neuroglobin - H00058157-P01-25 from Acris Antibodies
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Neuroglobin, Human Recombinant - 228-11156-1 from RayBiotech
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Recombinant Human NGB - 228-11156-2 from RayBiotech
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Recombinant Human NGB - 228-11156-3 from RayBiotech
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NGB fusion protein - ag4632 from Proteintech Group
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NGB fusion protein - Ag4325 from Proteintech Group
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Recombinant Human NGB - BP001004-CYT-450 from Syd Labs
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Recombinant Human Neuroglobin - NGB-127H from Creative Biomart
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Recombinant Human NGB - NGB-229H from Creative Biomart
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Neuroglobin Human - BCA-980 from Reagent Proteins
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Recombinant Neuroglobin (NGB) - RPA606Hu01 from Uscn Life Science Inc.
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Recombinant Neuroglobin (NGB) - RPA606Mu01 from Uscn Life Science Inc.
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Recombinant Neuroglobin (NGB) - RPA606Mu02 from Uscn Life Science Inc.
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Recombinant Neuroglobin (NGB) - RPA606Ra01 from Uscn Life Science Inc.
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Recombinant Neuroglobin (NGB) - RPA606Hu01 from Cloud-clone
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Recombinant Human Neuroglobin(NGB) - CSB-YP015776HU CSB-BP015776HU CSB-MP015776HU from Cusabio
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Recombinant human Neuroglobin - CSB-EP015776HU from Cusabio
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Neuroglobin Protein (Recombinant) - abx168296 from Abbexa
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Neuroglobin Protein (Recombinant) - abx263004 from Abbexa
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Neuroglobin - TP307482 from Acris Antibodies
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Recombinant Human NGB/Neuroglobin - CRN007A from Cell Science
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