NGB

Gene Symbol NGB
Entrez Gene 58157
Alt Symbol -
Species Human
Gene Type protein-coding
Description neuroglobin
Other Description -
Swissprots Q9NPG2
Accessions AAF62557 AAF63183 AAL98923 AAY16983 CAC12994 EAW81274 EAW81275 Q9NPG2 AF422797 AAL98924 AJ245946 CAC11133 AK098350 AK315395 BAG37788 BC032509 AAH32509 DQ890861 ABM81787 DQ894016 ABM84942 NM_021257 NP_067080
Function Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. {ECO:0000269|PubMed:11029004, ECO:0000269|PubMed:11473128, ECO:0000269|PubMed:18416560, ECO:0000269|PubMed:21190290, ECO:0000269|PubMed:21296891}.
Subcellular Location Perikaryon {ECO:0000250}. Cytoplasm. Mitochondrion.
Tissue Specificity Predominantly expressed in brain, the strongest expression is seen in the frontal lobe, the subthalamic nucleus and the thalamus. {ECO:0000269|PubMed:11029004}.

neuroglobin CRISPR/Cas9 KO Plasmid (h) - sc-401696 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

neuroglobin HDR Plasmid (h) - sc-401696-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

neuroglobin Double Nickase Plasmid (h) - sc-401696-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

neuroglobin Double Nickase Plasmid (h2) - sc-401696-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

neuroglobin CRISPR Activation Plasmid (h) - sc-401696-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

neuroglobin CRISPR Activation Plasmid (h2) - sc-401696-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

neuroglobin Lentiviral Activation Particles (h) - sc-401696-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

neuroglobin Lentiviral Activation Particles (h2) - sc-401696-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

neuroglobin siRNA (h) - sc-42081 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

neuroglobin shRNA Plasmid (h) - sc-42081-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

neuroglobin shRNA (h) Lentiviral Particles - sc-42081-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU057701 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15268 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15268 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NGB siRNA (Human) - CRJ1701 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Neuroglobin RNAi - H00058157-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

neuroglobin CRISPR/Cas9 KO Plasmid (h2) - sc-401696-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

neuroglobin HDR Plasmid (h2) - sc-401696-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human NGB (NM_021257.3) - SHH352080 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NGB(NM_021257.3) - SHR007458 from Creative biogene

Category siRNA
Species Reactivities Human

Human NGB siRNA - orb272202 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NGB shRNA Plasmid (Human) - CHJ1701 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NGB miRNA 3'UTR clone - MiUTR1H-06756 from Creative biogene

Species Reactivities Human
Search more