VPS26B

Gene Symbol	VPS26B
Entrez Gene	112936
Alt Symbol	Pep8b
Species	Human
Gene Type	protein-coding
Description	vacuolar protein sorting 26 homolog B (S. pombe)
Other Description	vacuolar protein sorting-associated protein 26B|vesicle protein sorting 26B
Swissprots	Q96A55 Q4G0F5
Accessions	EAW67825 EAW67826 EAW67827 Q4G0F5 AF452718 AAP13353 AV735504 BC007799 BC009747 AAH09747 BC013255 BC014128 AAH14128 BC098386 AAH98386 CD369199 EU176371 ABW03822 EU176709 ABW03510 XM_011542565 XP_011540867 NM_052875 NP_443107
Function	Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. May be involved in retrograde transport of SORT1 but not of IGF2R. Acts redundantly with VSP26
Subcellular Location	Cytoplasm {ECO:0000250|UniProtKB:Q8C0E2}. Membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8C0E2}. Early endosome {ECO:0000250|UniProtKB:Q8C0E2}. Late endosome {ECO:0000250|UniProtKB:Q8C0E2}. Note=Localizes to early and late endosomal structures (By similarity). {ECO:0000250|UniProtKB:Q8C0E2}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human VP26B full length protein - ab164988 from Abcam Category Protein Source Wheat germ Species Human

VPS26B Antibody Blocking Peptide - LS-E18863 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human VP26B Protein - H00112936-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

VPS26B Blocking Peptide - 33R-1235 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

VPS26B - H00112936-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

VPS26B - H00112936-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

VPS26B fusion protein - Ag8708 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

VPS26B fusion protein - Ag8929 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human VPS26B, GST-tagged - VPS26B-3674H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Vacuolar protein sorting-associated protein 26B(VPS26B) - CSB-YP676824HU CSB-EP676824HU CSB-BP676824HU CSB-MP676824HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

VPS26B - TP310499 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Vacuolar protein sorting-associated protein 26B(VPS26B) , Recombinant Protein - MBS1456991 from MyBioSource Category Protein Prices $1,730.00, $1,730.00, $2,195.00, $2,195.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

VP26B Recombinant Protein Antigen - NBP1-92575PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

VPS26B Peptide, Human - M34GP17311H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Human VPS26B Protein, MYC/DDK-tagged - VPS26B-492H from Creative Biomart Category Protein Source HEK293 Species Human

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