VPS26B

Gene Symbol	VPS26B
Entrez Gene	112936
Alt Symbol	Pep8b
Species	Human
Gene Type	protein-coding
Description	vacuolar protein sorting 26 homolog B (S. pombe)
Other Description	vacuolar protein sorting-associated protein 26B\|vesicle protein sorting 26B
Swissprots	Q96A55 Q4G0F5
Accessions	EAW67825 EAW67826 EAW67827 Q4G0F5 AF452718 AAP13353 AV735504 BC007799 BC009747 AAH09747 BC013255 BC014128 AAH14128 BC098386 AAH98386 CD369199 EU176371 ABW03822 EU176709 ABW03510 XM_011542565 XP_011540867 NM_052875 NP_443107
Function	Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. May be involved in retrograde transport of SORT1 but not of IGF2R. Acts redundantly with VSP26
Subcellular Location	Cytoplasm {ECO:0000250\|UniProtKB:Q8C0E2}. Membrane; Peripheral membrane protein {ECO:0000250\|UniProtKB:Q8C0E2}. Early endosome {ECO:0000250\|UniProtKB:Q8C0E2}. Late endosome {ECO:0000250\|UniProtKB:Q8C0E2}. Note=Localizes to early and late endosomal structures (By similarity). {ECO:0000250\|UniProtKB:Q8C0E2}.

VPS26B (C-13) - sc-109457 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

VPS26B (K-14) - sc-109458 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

VPS26B (P-24) - sc-134149 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	50 µg/0.5 ml
Host	Rabbit
Clonality	Polyclonal

VPS26B (P-24): sc-134149. Western blot analysis of VPS26B expression in 293T whole cell lysate.

Anti-VP26B antibody - ab74745 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VP26B antibody (ab74745) at 1 µg/ml + Fetal brain cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-VP26B antibody - ab74655 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-VP26B antibody (ab74655) at 1/500 dilutionLane 1 : LOVO cell extractsLane 2 : LOVO cell extracts with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-VPS26B Antibody (aa231-280) - LS-C120462 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of extracts from LOVO cells, using VPS26B Antibody. The lane on the right is treated with the synthesized peptide.

Anti-VPS26B Antibody (aa251-300) - LS-C82692 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Fetal brain cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

VP26B Antibody - NBP1-56502 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

VP26B Antibody - NBP1-92575 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: VP26B Antibody [NBP1-92575] - Staining of human kidney shows distinct membranous positivity in tubule cells.

Anti-VPS26B antibody produced in rabbit - HPA038172 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-VPS26B: <B>Cat. No. HPA038172</B>: Immunohistochemical staining of human kidney shows distinct membranous positivity in tubular cells.

Anti-VPS26B antibody produced in rabbit - SAB4500246 from Sigma-Aldrich

Prices	$335.50
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-VPS26B: <B>Cat. No. SAB4500246</B>: Immunoblotting analysis of extracts from LOVO cells, using Anti-VPS26B antibody. The lane on the left was treated with the Anti-VPS26B antibody. The lane on the right (negative control) was treated with both Anti-VPS26B antibody and the synthesized immunogen peptide.

VPS26B antibody - C-terminal region (ARP52439_P050) - ARP52439_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

VPS26B Antibody (OAAF04438) - OAAF04438 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

VPS26B antibody - 70R-21268 from Fitzgerald

Prices	$375.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

VPS26B Polyclonal Antibody - A5107 from ABclonal

Prices	$200.00, $480.00
Sizes	50 µg, 200 µg
Host	Rabbit
Clonality	Polyclonal

VPS26B antibody - 70R-3440 from Fitzgerald

Prices	$345.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

VPS26B Antibody - abx003908 from Abbexa

Host	Rabbit
Clonality	Polyclonal

VPS26B Antibody - abx014995 from Abbexa

Host	Rabbit
Clonality	Polyclonal

VPS26B antibody - 15915-1-AP from Acris Antibodies

Prices	$270.00
Sizes	150 µl
Host	Rabbit
Clonality	Polyclonal

Human brain tissue were subjected to SDS PAGE followed by western blot with 15915-1-AP(VPS26B antibody) at dilution of 1:1000

Anti-VPS26B, Polyclonal Antibody - 25-A5107 from ARP American Research Products

Prices	$279.00, $549.00
Sizes	50 µg, 200 µg
Host	Rabbit
Clonality	Polyclonal

VPS26B Antibody - 30-819 from ProSci

Prices	$315.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Antibody used in WB on Human Brain at 0.2-1 ug/ml.

VPS26B antibody - STJ27093 from St John's Laboratory Ltd

Host	Rabbit
Clonality	Polyclonal

Anti-VPS26B antibody - STJ96254 from St John's Laboratory Ltd

Host	Rabbit
Clonality	Polyclonal

VPS26B antibody - 15915-1-AP from Proteintech Group

Prices	$279.00
Sizes	con: 20 μg/150μl
Host	Rabbit
Clonality	Polyclonal

VPS26B - A5107 from NeoScientific

Prices	$480.00
Sizes	200 µg
Host	Rabbit
Clonality	Polyclonal

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