| Gene Symbol |
BCL11B
|
| Entrez Gene |
64919
|
| Alt Symbol |
ATL1, ATL1-alpha, ATL1-beta, ATL1-delta, ATL1-gamma, CTIP-2, CTIP2, RIT1, ZNF856B, hRIT1-alpha
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
B-cell CLL/lymphoma 11B (zinc finger protein)
|
| Other Description |
B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein|B-cell lymphoma/leukaemia 11B|B-cell lymphoma/leukemia 11B|BCL-11B|BCL11B/TRDC fusion|COUP-TF-interacting protein 2|hRit1|radiation-induced tumor suppressor gene 1 protein|zinc finger protein hRit1 alpha
|
| Swissprots |
Q9C0K0 Q9H162
|
| Accessions |
BAM78533 CAX20397 EAW81662 EAW81663 Q9C0K0 AB041218 BAM78282 AB043584 BAB32731 AB057668 BAM78283 AB057669 BAM78284 AB057670 BAM78285 AF086271 AJ404614 CAC17726 BC156139 AAI56140 XM_011537100 XP_011535402 NM_001282237 NP_001269166 NM_001282238 NP_001269167 NM_022898 NP_075049 NM_138576 NP_612808
|
| Function |
Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Tissue Specificity |
Highly expressed in brain and in malignant T- cell lines derived from patients with adult T-cell leukemia/lymphoma.
|