Gene Symbol | BCL11B |
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Entrez Gene | 64919 |
Alt Symbol | ATL1, ATL1-alpha, ATL1-beta, ATL1-delta, ATL1-gamma, CTIP-2, CTIP2, RIT1, ZNF856B, hRIT1-alpha |
Species | Human |
Gene Type | protein-coding |
Description | B-cell CLL/lymphoma 11B (zinc finger protein) |
Other Description | B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein|B-cell lymphoma/leukaemia 11B|B-cell lymphoma/leukemia 11B|BCL-11B|BCL11B/TRDC fusion|COUP-TF-interacting protein 2|hRit1|radiation-induced tumor suppressor gene 1 protein|zinc finger protein hRit1 alpha |
Swissprots | Q9C0K0 Q9H162 |
Accessions | BAM78533 CAX20397 EAW81662 EAW81663 Q9C0K0 AB041218 BAM78282 AB043584 BAB32731 AB057668 BAM78283 AB057669 BAM78284 AB057670 BAM78285 AF086271 AJ404614 CAC17726 BC156139 AAI56140 XM_011537100 XP_011535402 NM_001282237 NP_001269166 NM_001282238 NP_001269167 NM_022898 NP_075049 NM_138576 NP_612808 |
Function | Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Highly expressed in brain and in malignant T- cell lines derived from patients with adult T-cell leukemia/lymphoma. |
Human Ctip2 peptide - ab32404 from Abcam
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ATL1 Antibody Blocking Peptide - LS-E4481 from LifeSpan Bioscience
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ATL1 Antibody Blocking Peptide - LS-E23655 from LifeSpan Bioscience
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BCL11B Antibody Blocking Peptide - LS-E629 from LifeSpan Bioscience
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BCL11B Antibody Blocking Peptide - LS-E14451 from LifeSpan Bioscience
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BCL11B Antibody Blocking Peptide - LS-E11737 from LifeSpan Bioscience
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RIT1 Antibody Blocking Peptide - LS-E3332 from LifeSpan Bioscience
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RIT1 Antibody Blocking Peptide - LS-E22556 from LifeSpan Bioscience
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RIT1 Antibody Blocking Peptide - LS-E22557 from LifeSpan Bioscience
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Recombinant Human Rit1 Protein - H00006016-Q01 from Novus Biologicals
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Recombinant Human SPG3A Protein - H00051062-Q01 from Novus Biologicals
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BCL11B-Antibody-Center-Blocking-peptide - BP10966c from Abgent, a WuXi AppTec company
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RIT1 Blocking Peptide - 33R-10432 from Fitzgerald
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RIT1 Blocking Peptide - 33R-10324 from Fitzgerald
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RIT1 Blocking Peptide - abx063205 from Abbexa
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Recombinant Human BCL11B, His-tagged - BCL11B-28027TH from Creative Biomart
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ATL1 - PN201243 from Elabscience
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ATL1 - PN201247 from Elabscience
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Human ATL1 / SPG3A / Atlastin-1 Protein (GST Tag) - 10523-H09B-20 from Sino Biological
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Recombinant Human B-cell lymphoma/leukemia 11B(BCL11B) ,partial - CSB-YP880159HU CSB-EP880159HU CSB-BP880159HU CSB-MP880159HU from Cusabio
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Recombinant Human ATL1 / SPG3A / Atlastin-1 Protein (GST tag) - PKSH031549 from Elabscience
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BCL11B Recombinant Protein Antigen - NBP2-33549PEP from Novus Biologicals
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SPG3A Recombinant Protein Antigen - NBP1-90234PEP from Novus Biologicals
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ATL1 Peptide, Human - M34GP01111H from Creative Peptides
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BCL11B Peptide, Human - M34GP01369H from Creative Peptides
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