Gene Symbol | BCL11B |
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Entrez Gene | 64919 |
Alt Symbol | ATL1, ATL1-alpha, ATL1-beta, ATL1-delta, ATL1-gamma, CTIP-2, CTIP2, RIT1, ZNF856B, hRIT1-alpha |
Species | Human |
Gene Type | protein-coding |
Description | B-cell CLL/lymphoma 11B (zinc finger protein) |
Other Description | B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein|B-cell lymphoma/leukaemia 11B|B-cell lymphoma/leukemia 11B|BCL-11B|BCL11B/TRDC fusion|COUP-TF-interacting protein 2|hRit1|radiation-induced tumor suppressor gene 1 protein|zinc finger protein hRit1 alpha |
Swissprots | Q9C0K0 Q9H162 |
Accessions | BAM78533 CAX20397 EAW81662 EAW81663 Q9C0K0 AB041218 BAM78282 AB043584 BAB32731 AB057668 BAM78283 AB057669 BAM78284 AB057670 BAM78285 AF086271 AJ404614 CAC17726 BC156139 AAI56140 XM_011537100 XP_011535402 NM_001282237 NP_001269166 NM_001282238 NP_001269167 NM_022898 NP_075049 NM_138576 NP_612808 |
Function | Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Highly expressed in brain and in malignant T- cell lines derived from patients with adult T-cell leukemia/lymphoma. |
Bcl-11B (D6F1) XP ® Rabbit mAb - 12120 from Cell Signaling Technology
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Bcl-11a/b (C-19) - sc-33096 from Santa Cruz Biotechnology
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Bcl-11b (F-4) - sc-365320 from Santa Cruz Biotechnology
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Bcl-11b (F-5) - sc-365988 from Santa Cruz Biotechnology
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Bcl-11b (H-42) - sc-98513 from Santa Cruz Biotechnology
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Bcl-11b (E-15) - sc-103410 from Santa Cruz Biotechnology
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Anti-Ctip2 antibody - ab28448 from Abcam
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Anti-Ctip2 antibody - ab70453 from Abcam
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Anti-Ctip2 antibody - ab70452 from Abcam
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Anti-Ctip2 antibody - ab91044 from Abcam
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Anti-Ctip2 antibody - ab82701 from Abcam
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Anti-Ctip2 antibody [25B6] (FITC) - ab123449 from Abcam
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Anti-Ctip2 antibody [25B6] - ChIP Grade - ab18465 from Abcam
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Anti-Ctip2 antibody [EPR12275(2)] - ab187668 from Abcam
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Anti-BCL11B Antibody (aa500-550) - LS-C74740 from LifeSpan Bioscience
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Anti-BCL11B Antibody (C-Terminus) - LS-C74742 from LifeSpan Bioscience
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Anti-BCL11B Antibody (N-Terminus) - LS-C145036 from LifeSpan Bioscience
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Anti-BCL11B Antibody (N-Terminus) - LS-C145038 from LifeSpan Bioscience
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Anti-BCL11B Antibody (N-Terminus) - LS-C153383 from LifeSpan Bioscience
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Anti-BCL11B Antibody (aa307-334, AP) - LS-C252456 from LifeSpan Bioscience
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Anti-BCL11B Antibody (aa307-334, APC) - LS-C252457 from LifeSpan Bioscience
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Anti-BCL11B Antibody (aa307-334, FITC) - LS-C252459 from LifeSpan Bioscience
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Anti-BCL11B Antibody (aa307-334, Biotin) - LS-C252458 from LifeSpan Bioscience
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Anti-BCL11B Antibody (aa307-334, Azide-free, HRP) - LS-C252460 from LifeSpan Bioscience
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Anti-BCL11B Antibody (aa307-334, PE) - LS-C252461 from LifeSpan Bioscience
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