APOBEC3B

Gene Symbol	APOBEC3B
Entrez Gene	9582
Alt Symbol	A3B, APOBEC1L, ARCD3, ARP4, DJ742C19.2, PHRBNL, bK150C2.2
Species	Human
Gene Type	protein-coding
Description	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
Other Description	DNA dC->dU-editing enzyme APOBEC-3B|apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3B|cytidine deaminase|phorbolin 2|phorbolin 3|phorbolin-1-related protein|phorbolin-2/3|probable DNA dC->dU-editing enzyme APOBEC-3B
Swissprots	O95618 Q9UH17 Q7Z2N3 Q9UE74 Q5IFJ4 Q20WL1 Q7Z6D6 B0QYD2
Accessions	EAW60279 EAW60280 EAW60281 EAW60282 Q9UH17 AK024854 AU098564 AY743217 AAW31743 BC031803 BC053859 AAH53859 BX114955 CT841510 CAJ86440 CU012951 CAK54382 CU013031 CAK54462 CU013239 CAK54681 CU013319 CAK54761 KF651167 AHF72554 U61083 AAD00089 U61084 AAD00090 NM_001270411 NP_001257340 NM_004900 NP_004891
Function	DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double- stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV) and human T- cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of L
Subcellular Location	Nucleus {ECO:0000269|PubMed:16699599, ECO:0000269|PubMed:18667511, ECO:0000269|PubMed:21835787, ECO:0000269|PubMed:22915799}.
Tissue Specificity	Expressed at high and moderate levels in peripheral blood leukocytes, spleen, testes, heart, thymus, prostate and ovary. Also expressed at low levels in several other tissues. {ECO:0000269|PubMed:11863358, ECO:0000269|PubMed:20308164}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ARP4 (Angiopoietin-Like 4) Human ELISA Kit - ab99974 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 20 pg/ml Range 27.4 pg/ml - 20000 pg/ml

Human Cytidine Deaminase ELISA Kit - abx151238 from Abbexa Category ELISA Kit Sensitivity 0.28 ng/ml Range 0.781 ng/ml - 50 ng/ml

Angiopoietin Like Protein 4 (ANGPTL4), Human, ELISA Kit - SEB019Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.31ng/mL Range 0.78-50ng/mL

Cytidine Deaminase, ELISA Kit - MBS055018 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytidine Deaminase, ELISA Kit - MBS083701 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytidine Deaminase, ELISA Kit - MBS049146 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Probable DNA dC->dU-editing enzyme APOBEC-3B, ELISA Kit - MBS282376 from MyBioSource Category ELISA Kit Prices $425.00, $720.00, $3,160.00, $6,055.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytidine Deaminase, ELISA Kit - MBS073743 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytidine Deaminase, ELISA Kit - MBS106019 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytidine Deaminase, ELISA Kit - MBS049199 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytidine Deaminase, ELISA Kit - MBS096607 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Angiopoietin Like Protein 4 (ANGPTL4) - SEB019Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.29ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human Cytidine Deaminase (CDA) ELISA Kit - EKU03582 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.32 ng/mL Range 0.781-50 ng/mL

Human ANGPTL4(Angiopoietin Like Protein 4) ELISA Kit - E-EL-H0337 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.94 ng/mLng/mL Range 1.56~100 ng/mL

Human FABP4 (Fatty Acid Binding Protein 4, Adipocyte) CLIA Kit - E-CL-H0236 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.234ng/mL Range 0.391-25ng/mL

Human Cytidine deaminase ELISA Kit - abx251865 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Human Cytidine deaminase (CDA) ELISA Kit - EKC33368 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Human Cytidine deaminase ELISA Kit - EKE55212 from Biomatik Category ELISA Kit Prices $809.60, $3,440.80, $6,476.80 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.12 ng/mL Range 0.312-20 ng/mL

Human APOBEC3B ELISA Kit - E030757 from Biobool Category ELISA Kit

anti-APOBEC3B antibody - ARG57382 from Arigo Biolaboratories Category ELISA Kit

Probable DNA dC->dU-editing Enzyme APOBEC-3B (APOBEC3B), ELISA Kit - MBS9363505 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Probable DNA dC->dU-editing Enzyme APOBEC-3B (APOBEC3B), ELISA Kit - MBS9364827 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Probable DNA dC->dU-editing Enzyme APOBEC-3B (APOBEC3B), ELISA Kit - MBS9367015 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Probable DNA dC->dU-editing Enzyme APOBEC-3B (APOBEC3B), ELISA Kit - MBS9353252 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Probable DNA dC->dU-editing Enzyme APOBEC-3B (APOBEC3B), ELISA Kit - MBS9346871 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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