APOBEC3B

Gene Symbol	APOBEC3B
Entrez Gene	9582
Alt Symbol	A3B, APOBEC1L, ARCD3, ARP4, DJ742C19.2, PHRBNL, bK150C2.2
Species	Human
Gene Type	protein-coding
Description	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
Other Description	DNA dC->dU-editing enzyme APOBEC-3B|apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3B|cytidine deaminase|phorbolin 2|phorbolin 3|phorbolin-1-related protein|phorbolin-2/3|probable DNA dC->dU-editing enzyme APOBEC-3B
Swissprots	O95618 Q9UH17 Q7Z2N3 Q9UE74 Q5IFJ4 Q20WL1 Q7Z6D6 B0QYD2
Accessions	EAW60279 EAW60280 EAW60281 EAW60282 Q9UH17 AK024854 AU098564 AY743217 AAW31743 BC031803 BC053859 AAH53859 BX114955 CT841510 CAJ86440 CU012951 CAK54382 CU013031 CAK54462 CU013239 CAK54681 CU013319 CAK54761 KF651167 AHF72554 U61083 AAD00089 U61084 AAD00090 NM_001270411 NP_001257340 NM_004900 NP_004891
Function	DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double- stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV) and human T- cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of L
Subcellular Location	Nucleus {ECO:0000269|PubMed:16699599, ECO:0000269|PubMed:18667511, ECO:0000269|PubMed:21835787, ECO:0000269|PubMed:22915799}.
Tissue Specificity	Expressed at high and moderate levels in peripheral blood leukocytes, spleen, testes, heart, thymus, prostate and ovary. Also expressed at low levels in several other tissues. {ECO:0000269|PubMed:11863358, ECO:0000269|PubMed:20308164}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human APOBEC3B full length protein - ab160558 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

APOBEC3B Antibody Blocking Peptide - LS-E2504 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APOBEC3B Antibody Blocking Peptide - LS-E16812 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human APOBEC3B Protein - H00009582-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

APOBEC3B Peptide - P0355 from Novus Biologicals Category Peptide Species Human

APOBEC3B-PHO3-Antibody-C-term-Blocking-peptide - BP1353a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ApoBEC3B Blocking Peptide - 33R-6841 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

APOBEC3B - H00009582-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

APOBEC3B - H00009582-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Cytidine Deaminase, Human Recombinant - 228-12163-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Cytidine Deaminase Human - 228-12163-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Cytidine Deaminase Human - 228-12163-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

APOBEC3B Peptide - 7725P from ProSci Category Peptide Species Human

APOBEC3B fusion protein - ag6458 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

APOBEC3B fusion protein - ag6115 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

CDA Human - ENPS-014 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Cytidine Deaminase - BP000547-ENZ-007 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E.coli-derived. Species Human

CDA - JNV-RP1 from Reagent Proteins Category Protein Prices $364.00, $2,898.00 Sizes 20.00 µg, 1 mg Source E.coli

Recombinant Angiopoietin Like Protein 4 (ANGPTL4) - RPB019Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Probable DNA dC->dU-editing enzyme APOBEC-3B(APOBEC3B) - CSB-YP887025HU CSB-EP887025HU CSB-BP887025HU CSB-MP887025HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Cytidine deaminase(cdd) - CSB-YP004976YAS CSB-EP004976YAS CSB-BP004976YAS CSB-MP004976YAS from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Yersinia

Recombinant Cytidine deaminase(cdd) - CSB-YP004976SWW CSB-EP004976SWW CSB-BP004976SWW CSB-MP004976SWW from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Salmonella

Recombinant Cytidine deaminase(cdd) - CSB-YP004976VFI CSB-EP004976VFI CSB-BP004976VFI CSB-MP004976VFI from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Vibrio

Recombinant Cytidine deaminase(cdd) - CSB-YP004976VFE CSB-EP004976VFE CSB-BP004976VFE CSB-MP004976VFE from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Vibrio

Recombinant Cytidine deaminase(cdd) - CSB-YP004976YAH CSB-EP004976YAH CSB-BP004976YAH CSB-MP004976YAH from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Yersinia

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