Pmaip1

Gene Symbol Pmaip1
Entrez Gene 58801
Alt Symbol Noxa
Species Mouse
Gene Type protein-coding
Description phorbol-12-myristate-13-acetate-induced protein 1
Other Description protein Noxa
Swissprots Q9JM54
Accessions EDL09665 Q9JM54 AB041230 BAA95781 AK043856 BAC31682 AK088556 BAC40421 AK143990 BAE25650 AK169914 BAE41454 BC050821 AAH50821 NM_021451 NP_067426
Function Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1 (By similarity). Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1. {ECO:0000250, ECO:0000269|PubMed:10807576, ECO:0000269|PubMed:15694340, ECO:0000269|PubMed:15901672, ECO:0000269|PubMed:16822983, ECO:0000269|PubMed:17389404}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:10807576}.
Tissue Specificity Detected in thymocytes after irradiation with X-rays. Not detectable in untreated thymocytes (at protein level). Detected in embryonic neural precursor cells of the telencephalon Constitutively expressed at low levels in adult brain, testis, thymus, spleen, lung and kidney. {ECO:0000269|PubMed:16822983}.
Top Pathways p53 signaling pathway, Viral carcinogenesis

NOXA (FL-103) - sc-22764 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NOXA (FL-103): sc-22764. Immunofluorescence staining of normal mouse kidney frozen section showing cytoplasmic staining.

NOXA (K-16) - sc-11719 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NOXA (P-19) - sc-11718 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Noxa antibody - ab23563 from Abcam

Prices $372.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Noxa Antibody - NB100-56368 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

Noxa Antibody - NBP1-76763 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Noxa Antibody [NBP1-76763] - Human stomach tissue lysate with Noxa antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.

Noxa Antibody (69N15G8) - NBP2-25252 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 69N15G8
Western Blot: Noxa Antibody (69N15G8) [NBP2-25252] - Analysis of mouse A) Noxa recombinant protein, B) thymus and C) ovary using Noxa antibody at 1 ug/ml, 5 ug/ml and 5 ug/ml, respectively.

Noxa Antibody (69N15C9) - NBP2-25251 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 69N15C9
Western Blot: Noxa Antibody (69N15C9) [NBP2-25251] - Western blot analysis of mouse A) Noxa recombinant protein, B) thymus and C) ovary using Noxa antibody at 1ug/ml, 5 ug/ml and 5 ug/ml, respectively.

Noxa Antibody (69N15G8) [Azide Free] - NBP2-25267 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 69N15G8
Western Blot: Noxa Antibody (69N15G8) [Azide Free] [NBP2-25267] - Analysis of mouse A) Noxa recombinant protein, B) thymus and C) ovary using Noxa antibody at 1 ug/ml, 5 ug/ml and 5 ug/ml, respectively.

Noxa Antibody (69N15C9) [Azide Free] - NBP2-25266 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 69N15C9
Western Blot: Noxa Antibody (69N15C9) [Azide Free] [NBP2-25266] - Analysis of mouse A) Noxa recombinant protein, B) thymus and C) ovary using Noxa antibody at 1 ug/ml, 5 ug/ml and 5 ug/ml, respectively.

Noxa Antibody (69N15C9) [Alexa Fluor (R) 405] - NBP2-25266AF405 from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15C9

Noxa Antibody (69N15G8) [Alexa Fluor (R) 700] - NBP2-25267AF700 from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15G8

Noxa Antibody (69N15C9) [Alexa Fluor (R) 700] - NBP2-25266AF700 from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15C9

Noxa Antibody (69N15G8) [Alexa Fluor (R) 647] - NBP2-25267AF647 from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15G8

Noxa Antibody (69N15C9) [Alexa Fluor (R) 647] - NBP2-25266AF647 from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15C9

Noxa Antibody (69N15G8) [Alexa Fluor (R) 488] - NBP2-25267AF488 from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15G8

Noxa Antibody (69N15C9) [Alexa Fluor (R) 488] - NBP2-25266AF488 from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15C9

Noxa Antibody (69N15G8) [Alexa Fluor (R) 405] - NBP2-25267AF405 from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15G8

Noxa Antibody (69N15C9) [DyLight 405LS] - NBP2-25266V3 from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15C9

Noxa Antibody (69N15C9) [7C] - NBP2-25266V2 from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15C9

Noxa Antibody (69N15C9) [DyLight 405] - NBP2-25266V from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15C9

Noxa Antibody (69N15C9) [DyLight 350] - NBP2-25266UV from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15C9

Noxa Antibody (69N15C9) [DyLight 550] - NBP2-25266R from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15C9

Noxa Antibody (69N15C9) [PE] - NBP2-25266PE from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15C9

Noxa Antibody (69N15C9) [PerCP] - NBP2-25266PCP from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 69N15C9
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