RNASEH1

Gene Symbol RNASEH1
Entrez Gene 246243
Alt Symbol H1RNA, RNH1
Species Human
Gene Type protein-coding
Description ribonuclease H1
Other Description RNase H1|ribonuclease H type II
Swissprots O60857 O60930 Q6FHD4 O60523 Q5U0C1 B3KQU4 Q57Z93
Accessions AAX82026 ADP90574 ADP90575 ADP90576 ADP90577 ADP90578 ADP90579 ADP90580 ADP90581 ADP90582 ADP90583 ADP90584 ADP90585 ADP90586 ADP90587 ADP90588 ADP90589 ADP90590 ADP90591 ADP90592 ADP90593 ADP90594 ADP90595 ADP90596 ADP90597 ADP90598 ADP90599 ADP90600 ADP90601 ADP90602 ADP90603 ADP90604 ADP90605 ADP90606 ADP90607 ADP90608 ADP90609 ADP90610 ADP90611 ADP90612 ADP90613 EAX01061 O60930 AF039652 AAC09261 AF048994 AAC78563 AF048995 AAC78564 AJ224117 CAA11835 AK075490 BAG52156 AK096913 BAG53396 BC002973 AAH02973 BI553044 BT019670 AAV38476 CR541820 CAG46619 DA532761 DA612116 DQ892597 ABM83523 DQ895824 ABM86750 HG493504 HG493505 HG493506 HG493507 HG493508 XR_244873 XR_922665 XR_922666 XR_922667 XR_922668 XR_922669 XR_922670 XR_922671 XR_922672 XR_922673 XR_922674 NM_001286834 NP_001273763 NM_001286837 NP_001273766 NM_002936 NP_002927
Function Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (PubMed:10497183). Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II (PubMed:21700224). {ECO:0000269|PubMed:10497183, ECO:0000269|PubMed:21700224}.
Subcellular Location Cytoplasm {ECO:0000305}.
Tissue Specificity Ubiquitous.
Top Pathways DNA replication

RNase H1 (C-8) - sc-365057 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RNase H1 (C-8): sc-365057. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

RNase H1 (D-3) - sc-393802 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RNase H1 (D-3): sc-393802. Western blot analysis of RNase H1 expression in Jurkat (A) and PC-12 (B) whole cell lysates.

RNase H1 (H-147) - sc-292711 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

RNase H1 (H-4) - sc-376326 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RNase H1 (H-4): sc-376326. Western blot analysis of RNase H1 expression in non-transfected: sc-117752 (A) and mouse RNase H1 transfected: sc-123223 (B) 293T whole cell lysates.

RNase H1 (C-18) - sc-30319 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RNase H1 (C-18): sc-30319. Western blot analysis of RNase H1 expression in non-transfected: sc-117752 (A) and mouse RNase H1 transfected: sc-123223 (B) 293T whole cell lysates.

RNase H1 (H-9) - sc-365267 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RNase H1 (H-9): sc-365267. Western blot analysis of RNase H1 expression in non-transfected: sc-117752 (A) and mouse RNase H1 transfected: sc-123223 (B) 293T whole cell lysates.

RNase H1 (L-16) - sc-30318 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RNase H1 (L-16): sc-30318. Western blot analysis of RNase H1 expression in non-transfected: sc-117752 (A) and mouse RNase H1 transfected: sc-123223 (B) 293T whole cell lysates.

RNase H1 (30) - sc-136343 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RNase H1 (30): sc-136343. Western blot analysis of RNase H1 expression in Jurkat whole cell lysate.

RNase H1 (S-34) - sc-101114 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
RNase H1 (S-34): sc-101114. Western blot analysis of RNase H1 expression in non-transfected 293T: sc-117752 (A), human RNase H1 transfected 293T: sc-171572 (B) and HeLa (C) whole cell lysates.

Anti-RNase H1 antibody - ab56560 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
All lanes : Anti-RNase H1 antibody (ab56560) at 1 µg/mlLane 1 : Human fibroblasts whole cell lysate - untransfectedLane 2 : Human fibroblasts whole cell lysate - transfected with RnaseH constructLysates/proteins at 25 µg per lane.SecondaryHRP-conjugated sheep anti-mouse IgG polyclonal at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-RNase H1 antibody - ab83179 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-RNase H1 antibody (ab83179) at 1 µg/ml + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-RNASEH1 Antibody (aa7-461) - LS-C131910 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-RNASEH1 Antibody (aa189-287, Azide-free) - LS-C328521 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-RNASEH1 Antibody (C-Terminus) - LS-C101842 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
RNASEH1 antibody LS-C101842 Western blot of Jurkat lysate.

RNase H1 Antibody (5D10) - H00246243-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5D10

RNase H1 Antibody - NBP1-80448 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

RNase H1 Antibody - NBP2-38501 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: RNase H1 Antibody [NBP2-38501] - Staining of human kidney shows strong cytoplasmic positivity in distal tubules.

RNase H1 Antibody - NBP2-20171 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RNase H1 Antibody [NBP2-20171] - Whole zebrafish extract (30 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with RNase H1 antibody [N2C3] (NBP2-20171) diluted at 1:1000.

RNase H1 Antibody - H00246243-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

RNase H1 Antibody - H00246243-B01P-50ug from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-RNASEH1 antibody produced in mouse - SAB1412938 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
<B>Immunoblotting</B><BR/>Anti-RNASEH1:<B>Cat. No. SAB1412938</B>: Antibody concentration: 0.1–5 μg/mL. Immunofluorescence band of ~31.5 kDa using RNASEH1 transfected 293T lysate.<BR/><B>Lane</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-RNASEH1 antibody produced in rabbit - SAB2102013 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RNASEH1: <B>Cat. No.SAB2102013</B>: RNASEH1 in Jurkat cell lysate with RNASEH1 antibody at 1.0 μg/mL.

Anti-RNASEH1 antibody produced in rabbit - SAB2701325 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RNASEH1: <B>Cat. No. SAB2701325</B>: Immunohistochemical analysis of paraffin-embedded Breast carcinoma, using RNase H1 antibody at 1:500 dilution.

Monoclonal Anti-RNASEH1 antibody produced in mouse - WH0246243M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5D10
<B>Immunoblotting</B><BR/>Monoclonal Anti-RNASEH1, <B>Cat. No. WH0246243M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~32 kDa using HeLa lysate.

RNH1 Antibody (OAPA00309) - OAPA00309 from Aviva Systems Biology

Prices $100.00
Sizes 5 µg
Host Mouse
Clonality Monoclonal
Clone PAT1H23AT.
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