Gene Symbol | ACVR2A |
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Entrez Gene | 92 |
Alt Symbol | ACTRII, ACVR2 |
Species | Human |
Gene Type | protein-coding |
Description | activin A receptor, type IIA |
Other Description | activin receptor type-2A |
Swissprots | P27037 D3DP85 Q6NWV2 Q92474 Q53TH4 B4DWQ2 B2RAB8 |
Accessions | AAX93050 CCF77014 EAX11561 EAX11562 P27037 AA125825 AK301629 BAG63114 AK314124 BAG36815 AW162986 BC067416 BC067417 AAH67417 BC067418 AAH67418 BC069707 AAH69707 BG616903 BM503220 BU676046 BX645435 D31770 BAA06548 DA531622 DN918410 M93415 AAA35504 T07746 W03601 X62381 CAA44245 X63128 CAA44839 XM_005263843 XP_005263900 NM_001278579 NP_001265508 NM_001278580 NP_001265509 NM_001616 NP_001607 |
Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |
ACTR-IIA (A-24) - sc-130679 from Santa Cruz Biotechnology
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ACTR-II (149/1) - sc-57022 from Santa Cruz Biotechnology
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ACTR-II (D-15) - sc-5669 from Santa Cruz Biotechnology
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ACTR-II (F-12) - sc-390977 from Santa Cruz Biotechnology
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ACTR-II (H-65) - sc-25451 from Santa Cruz Biotechnology
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ACTR-IIA (N-17) - sc-5667 from Santa Cruz Biotechnology
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Anti-Activin Receptor Type IIA antibody - ab96793 from Abcam
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Anti-Activin Receptor Type IIA antibody - ab10595 from Abcam
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Anti-Activin Receptor Type IIA antibody [149/1] - ab18103 from Abcam
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Anti-Activin Receptor Type IIA antibody [149/1] - ab44923 from Abcam
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Anti-Activin Receptor Type IIA antibody [EPR7407] - ab134082 from Abcam
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Anti-Activin Receptor Type IIA antibody [MM0058-6J16] - ab78412 from Abcam
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Anti-Activin Receptor Type IIA antibody - N-terminal - ab135634 from Abcam
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Anti-ACVR2 / ACVR2A Antibody (Extracellular Domain, Biotin) - LS-C124887 from LifeSpan Bioscience
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Anti-ACVR2 / ACVR2A Antibody (Extracellular Domain) - LS-C122596 from LifeSpan Bioscience
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Anti-ACVR2 / ACVR2A Antibody (Extracellular Domain) - LS-C124888 from LifeSpan Bioscience
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Anti-ACVR2 / ACVR2A Antibody (Extracellular Domain, clone 12K5, APC) - LS-C182756 from LifeSpan Bioscience
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Anti-ACVR2 / ACVR2A Antibody (aa21-50, Biotin) - LS-C250804 from LifeSpan Bioscience
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Anti-ACVR2 / ACVR2A Antibody (aa21-50, AP) - LS-C250803 from LifeSpan Bioscience
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Anti-ACVR2 / ACVR2A Antibody (aa21-50, APC) - LS-C250805 from LifeSpan Bioscience
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Anti-ACVR2 / ACVR2A Antibody (aa21-50, FITC) - LS-C250806 from LifeSpan Bioscience
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Anti-ACVR2 / ACVR2A Antibody (aa21-50, Azide-free, HRP) - LS-C250807 from LifeSpan Bioscience
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Anti-ACVR2 / ACVR2A Antibody (aa267-513) - LS-C186343 from LifeSpan Bioscience
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Anti-ACVR2 / ACVR2A Antibody (His59) - LS-C177710 from LifeSpan Bioscience
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Anti-ACVR2 / ACVR2A Antibody (aa21-50, PE) - LS-C250808 from LifeSpan Bioscience
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