Gene Symbol | ACVR2A |
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Entrez Gene | 92 |
Alt Symbol | ACTRII, ACVR2 |
Species | Human |
Gene Type | protein-coding |
Description | activin A receptor, type IIA |
Other Description | activin receptor type-2A |
Swissprots | P27037 D3DP85 Q6NWV2 Q92474 Q53TH4 B4DWQ2 B2RAB8 |
Accessions | AAX93050 CCF77014 EAX11561 EAX11562 P27037 AA125825 AK301629 BAG63114 AK314124 BAG36815 AW162986 BC067416 BC067417 AAH67417 BC067418 AAH67418 BC069707 AAH69707 BG616903 BM503220 BU676046 BX645435 D31770 BAA06548 DA531622 DN918410 M93415 AAA35504 T07746 W03601 X62381 CAA44245 X63128 CAA44839 XM_005263843 XP_005263900 NM_001278579 NP_001265508 NM_001278580 NP_001265509 NM_001616 NP_001607 |
Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |
Human Activin Receptor Type IIA full length protein - ab114448 from Abcam
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Human Activin Receptor Type IIA protein fragment - ab114449 from Abcam
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Human Activin Receptor Type IIA protein fragment - ab152023 from Abcam
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Human Activin Receptor Type IIA protein fragment - ab125548 from Abcam
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ACVR2 / ACVR2A Antibody Blocking Peptide - LS-E3753 from LifeSpan Bioscience
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ACVR2 / ACVR2A Antibody Blocking Peptide - LS-E8693 from LifeSpan Bioscience
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Recombinant Human Activin RIIA Protein - H00000092-Q01 from Novus Biologicals
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Activin RIIA Recombinant Protein - H00000092-P01 from Novus Biologicals
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Activin RIIA Peptide - P2244 from Novus Biologicals
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ACVR2A-Antibody-N-term-Blocking-Peptide - BP7103a from Abgent, a WuXi AppTec company
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Recombinant Human Activin RIIA Fc Chimera - 340-R2-100 from R&D Systems
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Recombinant Human Activin RIIA Fc Chimera, CF - 340-R2-100/CF from R&D Systems
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Recombinant Human Activin RIIA Fc Chimera (CHO), CF - 340-RC2-100 from R&D Systems
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Human ACVR2A Fc tag protein - orb82851 from Biorbyt
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Human ACVR2A His tag protein - orb84010 from Biorbyt
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Human Activin RIIA protein - orb180164 from Biorbyt
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Human ACVR2A Protein - abx065140 from Abbexa
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Activin receptor type 2A (ACVR2A) - H00000092-P01-10 from Acris Antibodies
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Activin receptor type 2A (ACVR2A) - H00000092-P01-25 from Acris Antibodies
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Activin receptor type 2A (ACVR2A) - H00000092-Q01-10 from Acris Antibodies
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Activin receptor type 2A (ACVR2A) - H00000092-Q01-25 from Acris Antibodies
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Activin receptor type 2A (ACVR2A) - P5491 from Acris Antibodies
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Activin A Receptor Type II A (ACVR2A), Human - 20-8360 from ARP American Research Products
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Activin Receptor Type-2A, Activin RIIA, Human, Recombinant - 19-C561 from ARP American Research Products
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ACVR2A Recombinant Protein - 96-008 from ProSci
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