ACVR2A

Gene Symbol	ACVR2A
Entrez Gene	92
Alt Symbol	ACTRII, ACVR2
Species	Human
Gene Type	protein-coding
Description	activin A receptor, type IIA
Other Description	activin receptor type-2A
Swissprots	P27037 D3DP85 Q6NWV2 Q92474 Q53TH4 B4DWQ2 B2RAB8
Accessions	AAX93050 CCF77014 EAX11561 EAX11562 P27037 AA125825 AK301629 BAG63114 AK314124 BAG36815 AW162986 BC067416 BC067417 AAH67417 BC067418 AAH67418 BC069707 AAH69707 BG616903 BM503220 BU676046 BX645435 D31770 BAA06548 DA531622 DN918410 M93415 AAA35504 T07746 W03601 X62381 CAA44245 X63128 CAA44839 XM_005263843 XP_005263900 NM_001278579 NP_001265508 NM_001278580 NP_001265509 NM_001616 NP_001607
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ACTR-IIA CRISPR/Cas9 KO Plasmid (h) - sc-402524 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ACTR-IIA HDR Plasmid (h) - sc-402524-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ACTR-IIA Double Nickase Plasmid (h) - sc-402524-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ACTR-IIA Double Nickase Plasmid (h2) - sc-402524-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ACTR-IIA CRISPR Activation Plasmid (h) - sc-402524-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ACTR-IIA CRISPR Activation Plasmid (h2) - sc-402524-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ACTR-IIA Lentiviral Activation Particles (h) - sc-402524-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ACTR-IIA Lentiviral Activation Particles (h2) - sc-402524-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ACTR-IIA siRNA (h) - sc-40206 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ACTR-IIA shRNA Plasmid (h) - sc-40206-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ACTR-IIA shRNA (h) Lentiviral Particles - sc-40206-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU028601 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® siRNA - SIHK0042 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0040 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0041 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2796 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2796 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ACVR2A siRNA (Human) - CRH0058 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Activin RIIA RNAi - H00000092-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

ACVR2A - MBS8215246 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ACTR-IIA CRISPR/Cas9 KO Plasmid (h2) - sc-402524-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ACTR-IIA HDR Plasmid (h2) - sc-402524-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human ACVR2A (NM_001616.3) - SHH231250 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ACVR2A(NM_001616.3) - SHG037547 from Creative biogene Category siRNA Species Reactivities Human

ACVR2A shRNA Plasmid (Human) - CHH0058 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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