Gene Symbol | CCR1 |
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Entrez Gene | 1230 |
Alt Symbol | CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) receptor 1 |
Other Description | C-C CKR-1|C-C chemokine receptor type 1|CC-CKR-1|CCR-1|LD78 receptor|MIP-1alpha-R|RANTES receptor|RANTES-R|macrophage inflammatory protein 1-alpha receptor |
Swissprots | P32246 Q86VA9 |
Accessions | EAW64756 EAW64757 P32246 AI089760 BC051306 AAH51306 BC064991 AAH64991 BT019908 AAV38711 BT019909 AAV38712 BX337412 CK903574 D10925 BAA01723 EU831462 ACE87149 EU831549 ACE86468 L09230 AAA58408 L10918 AAA36543 NM_001295 NP_001286 |
Function | Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:18587271}; Multi-pass membrane protein {ECO:0000269|PubMed:18587271}. |
Tissue Specificity | Widely expressed in different hematopoietic cells. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
CKR-1 (C-20) - sc-6125 from Santa Cruz Biotechnology
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CKR-1 (H-52) - sc-7934 from Santa Cruz Biotechnology
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CKR-1 (S-15) - sc-31567 from Santa Cruz Biotechnology
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Anti-CCR1 antibody - ab13240 from Abcam
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Anti-CCR1 antibody - ab19013 from Abcam
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Anti-CCR1 antibody - ab117416 from Abcam
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Anti-CCR1 antibody [MM0061-7B17] - ab89055 from Abcam
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Anti-CCR1 antibody - F(ab)2 Fragment - ab1681 from Abcam
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Anti-CCR1 antibody - N-terminal - ab139399 from Abcam
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Anti-CCR1 antibody - N-terminal - ab140756 from Abcam
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Anti-CCR1 Antibody - LS-C48397 from LifeSpan Bioscience
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Anti-CCR1 Antibody (aa7-24) - LS-C78029 from LifeSpan Bioscience
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Anti-CCR1 Antibody - LS-C127286 from LifeSpan Bioscience
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Anti-CCR1 Antibody (aa1-34, clone 12K18) - LS-C182777 from LifeSpan Bioscience
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Anti-CCR1 Antibody (Extracellular Domain) IHC-plus⢠- LS-A1242 from LifeSpan Bioscience
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Anti-CCR1 Antibody (clone 141-2, PE) - LS-C179319 from LifeSpan Bioscience
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Anti-CCR1 Antibody (clone 11D85, APC) - LS-C183776 from LifeSpan Bioscience
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Anti-CCR1 Antibody (clone 11D86, FITC) - LS-C183777 from LifeSpan Bioscience
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Anti-CCR1 Antibody (clone 11D87, PE) - LS-C183778 from LifeSpan Bioscience
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Anti-CCR1 Antibody (aa7-24) - LS-C83939 from LifeSpan Bioscience
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Anti-CCR1 Antibody (aa341) - LS-C190185 from LifeSpan Bioscience
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Anti-CCR1 Antibody (aa1-30, AP) - LS-C253793 from LifeSpan Bioscience
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Anti-CCR1 Antibody (aa1-30, Biotin) - LS-C253795 from LifeSpan Bioscience
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Anti-CCR1 Antibody (aa1-30, APC) - LS-C253794 from LifeSpan Bioscience
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Anti-CCR1 Antibody (aa1-30, Azide-free, HRP) - LS-C253797 from LifeSpan Bioscience
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