Gene Symbol | CCR1 |
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Entrez Gene | 1230 |
Alt Symbol | CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) receptor 1 |
Other Description | C-C CKR-1|C-C chemokine receptor type 1|CC-CKR-1|CCR-1|LD78 receptor|MIP-1alpha-R|RANTES receptor|RANTES-R|macrophage inflammatory protein 1-alpha receptor |
Swissprots | P32246 Q86VA9 |
Accessions | EAW64756 EAW64757 P32246 AI089760 BC051306 AAH51306 BC064991 AAH64991 BT019908 AAV38711 BT019909 AAV38712 BX337412 CK903574 D10925 BAA01723 EU831462 ACE87149 EU831549 ACE86468 L09230 AAA58408 L10918 AAA36543 NM_001295 NP_001286 |
Function | Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:18587271}; Multi-pass membrane protein {ECO:0000269|PubMed:18587271}. |
Tissue Specificity | Widely expressed in different hematopoietic cells. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
CCR1 Antibody Blocking Peptide - LS-E28677 from LifeSpan Bioscience
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CCR1 Antibody Blocking Peptide - LS-E7616 from LifeSpan Bioscience
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CCR1 Antibody Blocking Peptide - LS-E28196 from LifeSpan Bioscience
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CCR1-Antibody-C-term-Blocking-peptide - BP12775b from Abgent, a WuXi AppTec company
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CCR1-Antibody-N-term-Blocking-Peptide - BP4859a from Abgent, a WuXi AppTec company
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CCR1 Protein - GTX108988-pro from GeneTex
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CCR1 Blocking Peptide - 33R-10751 from Fitzgerald
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CD191 / CCR1 - H00001230-G01 from Acris Antibodies
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CD191 / CCR1 - H00001230-Q01-10 from Acris Antibodies
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CD191 / CCR1 - H00001230-Q01-25 from Acris Antibodies
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CD191 / CCR1 Control Peptide - AP09936CP-N from Acris Antibodies
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CCR1 fusion protein - ag14563 from Proteintech Group
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CCR1 fusion protein - ag14538 from Proteintech Group
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Recombinant Chemokine C-C-Motif Receptor 1 (CCR1) - RPB534Hu01 from Uscn Life Science Inc.
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Recombinant Chemokine C-C-Motif Receptor 1 (CCR1) - RPB534Mu01 from Uscn Life Science Inc.
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Recombinant Chemokine C-C-Motif Receptor 1 (CCR1) - RPB534Mu02 from Uscn Life Science Inc.
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ChemiSCREEN™ CCR1 Membrane Preparation - HTS005M from EMD Millipore
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Recombinant Chemokine C-C-Motif Receptor 1 (CCR1) - RPB534Hu01 from Cloud-clone
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CCR1 Blocking Peptide - 3414BP-50 from Biovision
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CCR1 Recombinant Protein - H00001230-G01 from Novus Biologicals
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C-C chemokine receptor type 1 (CCR1), Recombinant Protein - MBS718679 from MyBioSource
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CCR1, Peptide - MBS843756 from MyBioSource
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CCR1-Blocking-Peptide-C-term - BP21344b from Abgent, a WuXi AppTec company
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CCR1-Blocking-Peptide-N-term - BP21343a from Abgent, a WuXi AppTec company
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CCR1 Peptide, Human - M34GP02670H from Creative Peptides
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