EXOSC7

Gene Symbol	EXOSC7
Entrez Gene	23016
Alt Symbol	EAP1, RRP42, Rrp42p, hRrp42p, p8
Species	Human
Gene Type	protein-coding
Description	exosome component 7
Other Description	exosome complex component RRP42|exosome complex exonuclease RRP42|ribosomal RNA-processing protein 42
Swissprots	Q96E72 Q15024
Accessions	EAW64731 EAW64732 EAW64733 EAW64734 Q15024 AK090511 AK130053 AK295779 BAG58602 AK315741 BAG38096 BC012831 AAH12831 BU153856 D29958 BAA06226 XR_245104 XR_940394 NM_015004 NP_055819 NR_023353
Function	Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways
Subcellular Location	Nucleus, nucleolus {ECO:0000269|PubMed:11812149}. Cytoplasm {ECO:0000305|PubMed:11812149}. Nucleus {ECO:0000305|PubMed:11812149}.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

exosome component 7, ELISA Kit - MBS9333352 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Exosome Component 7 (EXOSC7) - SEM477Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.065ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Exosome Component 7 (EXOSC7) - SEM477Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.065ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Exosome Component 7 (EXOSC7), ELISA Kit - MBS2025541 from MyBioSource Category ELISA Kit Prices $410.00, $610.00, $830.00, $3,420.00, $6,200.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of EXOSC7 is typically less than 0.065ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

Human Exosome Component 7 ELISA Kit - abx258177 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human EXOSC7 ELISA Kit (Sandwich ELISA) - LS-F25606 from LifeSpan Bioscience Category ELISA Kit Prices $850.00 Sizes 1 plate Sensitivity 0.065 ng/ml Range 0.156-10 ng/ml

Human Exosome Component 7 (EXOSC7) ELISA Kit - EKU09336 from Biomatik Category ELISA Kit Prices $809.00, $3,557.00, $6,468.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.065 ng/mL Range 0.156-10 ng/mL

Human EXOSC7 ELISA Kit - E013853 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of EXOSC7 is typically less than 0.065ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding t

EXOSC7 ELISA Kit (Human) (OKCD02074) - OKCD02074 from Aviva Systems Biology Category ELISA Kit Prices $585.00 Sizes 96 wells Sensitivity < 0.065 ng/mL Range 0.156 - 10 ng/mL

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