Gene Symbol | FANCM |
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Entrez Gene | 57697 |
Alt Symbol | FAAP250, KIAA1596 |
Species | Human |
Gene Type | protein-coding |
Description | Fanconi anemia, complementation group M |
Other Description | ATP-dependent RNA helicase FANCM|Fanconi anemia group M protein|fanconi anemia-associated polypeptide of 250 kDa|protein Hef ortholog |
Swissprots | Q3YFH9 B2RTQ9 Q8IYD8 Q9HCH6 Q8N9X6 |
Accessions | EAW65781 EAW65782 EAW65783 EAW65784 Q8IYD8 AB046816 BAB13422 AK001672 AK093422 BAC04159 AL833656 BC036056 AAH36056 BC140776 AAI40777 BC144511 AAI44512 BC156490 AAI56491 BX500546 DQ140356 AAZ53290 JF432109 ADZ15326 XM_005267929 XP_005267986 XM_011537034 XP_011535336 XM_011537035 XP_011535337 XM_011537036 XP_011535338 XM_011537037 XP_011535339 NM_001308133 NP_001295062 NM_001308134 NP_001295063 NM_020937 NP_065988 |
Function | ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. {ECO:0000269|PubMed:16116422, ECO:0000269|PubMed:16116434, ECO:0000269|Ref.8, ECO:0000269|Ref.9}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16116422, ECO:0000269|Ref.8, ECO:0000269|Ref.9}. |
Top Pathways | Fanconi anemia pathway |
Human FANCM full length protein - ab132334 from Abcam
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Human FANCM peptide - ab27788 from Abcam
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FANCM Antibody Blocking Peptide - LS-E27349 from LifeSpan Bioscience
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Recombinant Human FANCM Protein - H00057697-P01 from Novus Biologicals
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FANCM blocking peptide - GTX88116-PEP from GeneTex
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FANCM Peptide - AC21-2173-P from Abcore
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FANCM - H00057697-P01 from Acris Antibodies
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FANCM Peptide - 42-572P from ProSci
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FANCM fusion protein - ag3618 from Proteintech Group
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Recombinant Human Fanconi anemia group M protein(FANCM) ,partial - CSB-YP810301HU CSB-EP810301HU CSB-BP810301HU CSB-MP810301HU from Cusabio
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FANCM Protein - abx163641 from Abbexa
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FANCM, Peptide - MBS427292 from MyBioSource
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FANCM-Blocking-Peptide-C-Term - BP21872b from Abgent, a WuXi AppTec company
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FANCM Peptide, Human - M34GP05529H from Creative Peptides
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Fanconi anemia group M protein (FANCM), partial, Recombinant Protein - MBS1301099 from MyBioSource
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FANCM Recombinant Protein Antigen - NBP2-55444PEP from Novus Biologicals
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FANCM Immunizing peptide - orb59825 from Biorbyt
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