Gene Symbol | FANCM |
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Entrez Gene | 57697 |
Alt Symbol | FAAP250, KIAA1596 |
Species | Human |
Gene Type | protein-coding |
Description | Fanconi anemia, complementation group M |
Other Description | ATP-dependent RNA helicase FANCM|Fanconi anemia group M protein|fanconi anemia-associated polypeptide of 250 kDa|protein Hef ortholog |
Swissprots | Q3YFH9 B2RTQ9 Q8IYD8 Q9HCH6 Q8N9X6 |
Accessions | EAW65781 EAW65782 EAW65783 EAW65784 Q8IYD8 AB046816 BAB13422 AK001672 AK093422 BAC04159 AL833656 BC036056 AAH36056 BC140776 AAI40777 BC144511 AAI44512 BC156490 AAI56491 BX500546 DQ140356 AAZ53290 JF432109 ADZ15326 XM_005267929 XP_005267986 XM_011537034 XP_011535336 XM_011537035 XP_011535337 XM_011537036 XP_011535338 XM_011537037 XP_011535339 NM_001308133 NP_001295062 NM_001308134 NP_001295063 NM_020937 NP_065988 |
Function | ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. {ECO:0000269|PubMed:16116422, ECO:0000269|PubMed:16116434, ECO:0000269|Ref.8, ECO:0000269|Ref.9}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16116422, ECO:0000269|Ref.8, ECO:0000269|Ref.9}. |
Top Pathways | Fanconi anemia pathway |
FANCM (E-17) - sc-70275 from Santa Cruz Biotechnology
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FANCM (H-300) - sc-98710 from Santa Cruz Biotechnology
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FANCM (M40-P2C6) - sc-101389 from Santa Cruz Biotechnology
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FANCM (N-15) - sc-70277 from Santa Cruz Biotechnology
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Anti-FANCM antibody - ab95014 from Abcam
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Anti-FANCM antibody - ab26272 from Abcam
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Anti-FANCM antibody - ab97905 from Abcam
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Anti-FANCM antibody - ab95086 from Abcam
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Anti-FANCM antibody - ab167214 from Abcam
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Anti-FANCM Antibody (aa1159-1171) - LS-C112993 from LifeSpan Bioscience
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Anti-FANCM Antibody (aa1-50) - LS-C289361 from LifeSpan Bioscience
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Anti-FANCM Antibody - LS-C307475 from LifeSpan Bioscience
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Anti-FANCM Antibody (aa1100-1200) - LS-C83818 from LifeSpan Bioscience
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FANCM Antibody - NB110-98674 from Novus Biologicals
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FANCM Antibody - H00057697-B01P from Novus Biologicals
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FANCM Antibody - NBP1-49890 from Novus Biologicals
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FANCM Antibody [FITC] - NB110-98674F from Novus Biologicals
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FANCM Antibody [DyLight 405] - NB110-98674V from Novus Biologicals
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FANCM Polyclonal Antibody - bs-13143R from Bioss
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FANCM Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13143R-A350 from Bioss
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FANCM Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13143R-A488 from Bioss
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FANCM Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13143R-A555 from Bioss
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FANCM Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13143R-A647 from Bioss
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FANCM Polyclonal Antibody, Cy3 Conjugated - bs-13143R-Cy3 from Bioss
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FANCM Polyclonal Antibody, Cy5 Conjugated - bs-13143R-Cy5 from Bioss
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