FANCM

Gene Symbol FANCM
Entrez Gene 57697
Alt Symbol FAAP250, KIAA1596
Species Human
Gene Type protein-coding
Description Fanconi anemia, complementation group M
Other Description ATP-dependent RNA helicase FANCM|Fanconi anemia group M protein|fanconi anemia-associated polypeptide of 250 kDa|protein Hef ortholog
Swissprots Q3YFH9 B2RTQ9 Q8IYD8 Q9HCH6 Q8N9X6
Accessions EAW65781 EAW65782 EAW65783 EAW65784 Q8IYD8 AB046816 BAB13422 AK001672 AK093422 BAC04159 AL833656 BC036056 AAH36056 BC140776 AAI40777 BC144511 AAI44512 BC156490 AAI56491 BX500546 DQ140356 AAZ53290 JF432109 ADZ15326 XM_005267929 XP_005267986 XM_011537034 XP_011535336 XM_011537035 XP_011535337 XM_011537036 XP_011535338 XM_011537037 XP_011535339 NM_001308133 NP_001295062 NM_001308134 NP_001295063 NM_020937 NP_065988
Function ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. {ECO:0000269|PubMed:16116422, ECO:0000269|PubMed:16116434, ECO:0000269|Ref.8, ECO:0000269|Ref.9}.
Subcellular Location Nucleus {ECO:0000269|PubMed:16116422, ECO:0000269|Ref.8, ECO:0000269|Ref.9}.
Top Pathways Fanconi anemia pathway

FANCM CRISPR/Cas9 KO Plasmid (h) - sc-403495 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FANCM HDR Plasmid (h) - sc-403495-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FANCM Double Nickase Plasmid (h) - sc-403495-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FANCM Double Nickase Plasmid (h2) - sc-403495-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FANCM CRISPR Activation Plasmid (h) - sc-403495-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FANCM CRISPR Activation Plasmid (h2) - sc-403495-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FANCM Lentiviral Activation Particles (h) - sc-403495-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FANCM Lentiviral Activation Particles (h2) - sc-403495-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FANCM siRNA (h) - sc-77313 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FANCM shRNA Plasmid (h) - sc-77313-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FANCM shRNA (h) Lentiviral Particles - sc-77313-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN8478 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8478 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06665 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06665

FANCM siRNA (Human) - CRJ1640 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FANCM - MBS8229780 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FANCM (NM_020937.2) - SHH292357 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FANCM(NM_020937.2) - SHH049115 from Creative biogene

Category siRNA
Species Reactivities Human

Human FANCM siRNA - orb272141 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FANCM shRNA Plasmid (Human) - CHJ1640 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FANCM miRNA 3'UTR clone - MiUTR1H-03512 from Creative biogene

Species Reactivities Human
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