NPEPPS

Gene Symbol	NPEPPS
Entrez Gene	9520
Alt Symbol	AAP-S, MP100, PSA
Species	Human
Gene Type	protein-coding
Description	aminopeptidase puromycin sensitive
Other Description	cytosol alanyl aminopeptidase|metalloproteinase MP100|puromycin-sensitive aminopeptidase
Swissprots	Q9NP16 P55786 Q6P145 B7Z463 Q9UEM2
Accessions	AAF70086 EAW94811 EAW94812 EAW94813 P55786 AA864462 AJ132583 CAA10709 AK095877 BAG53154 AK096491 AK096709 BAG53355 AK293450 BAH11510 AK293995 BAH11645 AK296887 BAH12449 AK297107 BAH12498 AK303037 BAH13885 AK311414 BC065294 AAH65294 BM723238 DB476543 XM_011525496 XP_011523798 NM_006310 NP_006301
Function	Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. {ECO:0000269|PubMed:10978616, ECO:0000269|PubMed:11062501, ECO:0000269|PubMed:17154549, ECO:0000269|PubMed:17318184, ECO:0000269|PubMed:19917696}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000269|PubMed:10978616}. Nucleus {ECO:0000305}.
Tissue Specificity	Detected in liver, epithelium of renal tubules, epithelium of small and large intestine, gastric epithelial cells, and alveoli of the lung (at protein level). {ECO:0000269|PubMed:10978616}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PSA (LT3D2) - sc-101384 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

PSAP (E-5) - sc-390184 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

PSAP (N-20) - sc-26023 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

PSAP (C-18) - sc-26025 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

PSAP (H-300) - sc-292968 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-NPEPPS antibody - ab77643 from Abcam Prices $370.00 Sizes 200 µl Host Goat Clonality Polyclonal

Anti-NPEPPS antibody - ab96066 from Abcam Prices $370.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-NPEPPS antibody [2649C4a] - ab76558 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2649C4a

Anti-NPEPPS Antibody - LS-C34948 from LifeSpan Bioscience Prices $445.00 Sizes 50 µl Host Goat Clonality Polyclonal

Anti-NPEPPS Antibody - LS-C126060 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Mouse Clonality Monoclonal

Anti-NPEPPS Antibody (clone 2649C4a) - LS-C184704 from LifeSpan Bioscience Prices $335.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 2649C4a

Anti-NPEPPS Antibody (aa584-793, Biotin) - LS-C299765 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-NPEPPS Antibody (aa819-833) - LS-C61767 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-NPEPPS Antibody (aa584-755, Biotin) - LS-C299767 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-NPEPPS Antibody (aa141-272, Biotin) - LS-C300074 from LifeSpan Bioscience Prices $425.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-NPEPPS Antibody (aa584-793, FITC) - LS-C303185 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-NPEPPS Antibody (aa584-755, FITC) - LS-C303187 from LifeSpan Bioscience Prices $465.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-NPEPPS Antibody (aa141-272, FITC) - LS-C304639 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-NPEPPS Antibody (aa141-272) - LS-C296157 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-NPEPPS Antibody (aa584-755) - LS-C296152 from LifeSpan Bioscience Prices $415.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-NPEPPS Antibody (aa584-793) - LS-C296151 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-NPEPPS Antibody (aa709-737) - LS-C99291 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-NPEPPS Antibody (clone 2649C4a) - LS-C342737 from LifeSpan Bioscience Prices $375.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 2649C4a

Anti-NPEPPS Antibody (aa328-648) IHC-plus™ - LS-B10860 from LifeSpan Bioscience Prices $395.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Kallikrein 3/PSA Antibody - NB200-135 from Novus Biologicals Prices $279.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

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