NPEPPS

Gene Symbol NPEPPS
Entrez Gene 9520
Alt Symbol AAP-S, MP100, PSA
Species Human
Gene Type protein-coding
Description aminopeptidase puromycin sensitive
Other Description cytosol alanyl aminopeptidase|metalloproteinase MP100|puromycin-sensitive aminopeptidase
Swissprots Q9NP16 P55786 Q6P145 B7Z463 Q9UEM2
Accessions AAF70086 EAW94811 EAW94812 EAW94813 P55786 AA864462 AJ132583 CAA10709 AK095877 BAG53154 AK096491 AK096709 BAG53355 AK293450 BAH11510 AK293995 BAH11645 AK296887 BAH12449 AK297107 BAH12498 AK303037 BAH13885 AK311414 BC065294 AAH65294 BM723238 DB476543 XM_011525496 XP_011523798 NM_006310 NP_006301
Function Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. {ECO:0000269|PubMed:10978616, ECO:0000269|PubMed:11062501, ECO:0000269|PubMed:17154549, ECO:0000269|PubMed:17318184, ECO:0000269|PubMed:19917696}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:10978616}. Nucleus {ECO:0000305}.
Tissue Specificity Detected in liver, epithelium of renal tubules, epithelium of small and large intestine, gastric epithelial cells, and alveoli of the lung (at protein level). {ECO:0000269|PubMed:10978616}.

PSAP CRISPR/Cas9 KO Plasmid (h) - sc-405857 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSAP HDR Plasmid (h) - sc-405857-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSAP Double Nickase Plasmid (h) - sc-405857-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSAP Double Nickase Plasmid (h2) - sc-405857-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSAP CRISPR Activation Plasmid (h) - sc-405857-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSAP CRISPR Activation Plasmid (h2) - sc-405857-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSAP Lentiviral Activation Particles (h) - sc-405857-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSAP Lentiviral Activation Particles (h2) - sc-405857-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSAP siRNA (h) - sc-44046 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PSAP shRNA Plasmid (h) - sc-44046-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PSAP shRNA (h) Lentiviral Particles - sc-44046-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Puromycin-sensitive aminopeptidase/NPEPPS RNAi - H00009520-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU110251 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15447 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15447 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09230 from Sigma-Aldrich

Category miRNA

NPEPPS siRNA (Human) - CRH6326 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NPEPPS(NM_006310.3) - SHR017950 from Creative biogene

Category siRNA
Species Reactivities Human

Human NPEPPS siRNA - orb266828 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NPEPPS shRNA Plasmid (Human) - CHH6326 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NPEPPS miRNA 3'UTR clone - MiUTR1H-06875 from Creative biogene

Species Reactivities Human
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