NPEPPS

Gene Symbol	NPEPPS
Entrez Gene	9520
Alt Symbol	AAP-S, MP100, PSA
Species	Human
Gene Type	protein-coding
Description	aminopeptidase puromycin sensitive
Other Description	cytosol alanyl aminopeptidase|metalloproteinase MP100|puromycin-sensitive aminopeptidase
Swissprots	Q9NP16 P55786 Q6P145 B7Z463 Q9UEM2
Accessions	AAF70086 EAW94811 EAW94812 EAW94813 P55786 AA864462 AJ132583 CAA10709 AK095877 BAG53154 AK096491 AK096709 BAG53355 AK293450 BAH11510 AK293995 BAH11645 AK296887 BAH12449 AK297107 BAH12498 AK303037 BAH13885 AK311414 BC065294 AAH65294 BM723238 DB476543 XM_011525496 XP_011523798 NM_006310 NP_006301
Function	Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. {ECO:0000269|PubMed:10978616, ECO:0000269|PubMed:11062501, ECO:0000269|PubMed:17154549, ECO:0000269|PubMed:17318184, ECO:0000269|PubMed:19917696}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000269|PubMed:10978616}. Nucleus {ECO:0000305}.
Tissue Specificity	Detected in liver, epithelium of renal tubules, epithelium of small and large intestine, gastric epithelial cells, and alveoli of the lung (at protein level). {ECO:0000269|PubMed:10978616}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NPEPPS protein fragment - ab160527 from Abcam Category Protein Source Wheat germ Species Human

KLK3 / PSA Antibody Blocking Peptide - LS-E8206 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLK3 / PSA Antibody Blocking Peptide - LS-E15412 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NPEPPS Antibody Blocking Peptide - LS-E8290 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NPEPPS Antibody Blocking Peptide - LS-E26507 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Puromycin-sensitive aminopeptidase/NPEPPS Partial Recombinant Protein - H00009520-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PSA-Antibody-C-term-Blocking-Peptide - BP6563b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NPEPPS blocking peptide - GTX88877-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

Recombinant Human NPEPPS, CF - 6410-ZN-010 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Pro46-Val919, with an N-terminal Met and a C-terminal 10-His tag

PSA protein - orb107900 from Biorbyt Category Protein Prices $306.00 Sizes 100 μg Species Human

PSA protein - orb107913 from Biorbyt Category Protein Prices $918.00 Sizes 100 μg Species Human

PSA protein - orb79682 from Biorbyt Category Protein Prices $638.00, $1,207.00, $1,564.00 Sizes 100 µg, 500 µg, 1 mg

PSA protein (> 40% pure) - 30C-CP1017P from Fitzgerald Category Protein Prices $195.00 Sizes 1 mg

PSA protein (> 75% pure) - 30-AP16S from Fitzgerald Category Protein Prices $107.00 Sizes 100 µg

PSA protein (> 95% pure) - 30C-CP1099 from Fitzgerald Category Protein Prices $250.80 Sizes 100 µg

PSA protein (> 95% pure) - 30C-CP1017 from Fitzgerald Category Protein Prices $125.00, $395.00 Sizes 100 µg, 1 mg

PSA protein (> 95% pure) - 30C-CP1105 from Fitzgerald Category Protein Prices $370.80 Sizes 100 µg

PSA protein (> 95% pure) - 30C-CP1118 from Fitzgerald Category Protein Prices $180.00 Sizes 100 µg

PSA protein (> 98% pure) - 30C-CP1017U from Fitzgerald Category Protein Prices $195.00, $495.00 Sizes 100 µg, 1 mg

PSA/ACT complex protein - 30-AP13 from Fitzgerald Category Protein Prices $650.00 Sizes 50 µg

PSA/ACT complex protein - 30R-AP022 from Fitzgerald Category Protein Prices $1,250.00 Sizes 100 µg

PSA/ACT complex protein - 30-AP21 from Fitzgerald Category Protein Prices $400.00 Sizes 50 µg

PSA/ACT complex protein - 30C-CP1097 from Fitzgerald Category Protein Prices $502.80 Sizes 50 µg

Human PSA Protein - abx060983 from Abbexa Category Protein Source Human Seminal Fluid

Human PSA Protein - abx060984 from Abbexa Category Protein Source Human Fluids

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