DOK4

Gene Symbol DOK4
Entrez Gene 55715
Alt Symbol -
Species Human
Gene Type protein-coding
Description docking protein 4
Other Description IRS-5|IRS5|downstream of tyrosine kinase 4|insulin receptor substrate 5
Swissprots Q9BTP2 Q9NVV3 O75209 Q8TEW6
Accessions AAC24310 EAW82932 EAW82933 EAW82934 Q8TEW6 AF466369 AAL74195 AK001350 BAA91642 AK307270 AK315426 BAG37814 AW163719 BC001540 AAH01540 BC003541 AAH03541 DQ893008 ABM83934 DQ896254 ABM87253 XM_005256042 XP_005256099 XM_005256043 XP_005256100 XM_011523226 XP_011521528 NM_018110 NP_060580
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. {ECO:0000250}.
Tissue Specificity Widely expressed. High expression in skeletal muscle, heart, kidney and liver. Weaker expression in spleen, lung and small intestine, brain, heart and. Expressed in both resting and activated peripheral blood T-cells. {ECO:0000269|PubMed:12595900, ECO:0000269|PubMed:12730241}.

Dok-4 (C-16) - sc-130133 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Dok-4 (C-16): sc-130133. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.

Dok-4 (C-17) - sc-27483 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-DOK4 antibody - ab175624 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse kidney tissue labelling DOK4 with ab175624 at 1/200. Magnification: 200x.

Anti-DOK4 antibody - ab60223 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab60223 at 1/50 dilution, staining DOK4 in human breast carcinoma by Immunohistochemistry, Formalin fixed, Paraffin embedded tissue, followed by peroxidase conjugated secondary antibody and AEC staining.

Anti-DOK4 antibody - ab64841 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DOK4 antibody (ab64841) at 1/500 dilutionLane 1 : Extracts of 293 cellsLane 2 : Extracts of Mouse lung cellsLane 3 : Extracts of Mouse lung cells with immunising peptide

Anti-DOK4 Antibody (C-Terminus, PE) - LS-C276857 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK4 Antibody (C-Terminus, Azide-free, HRP) - LS-C276856 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK4 Antibody (C-Terminus) - LS-C135748 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DOK4 antibody LS-C135748 Western blot of Fetal Heart lysate.

Anti-DOK4 Antibody (C-Terminus) - LS-C327212 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK4 Antibody (aa38-87) - LS-C135749 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DOK4 antibody LS-C135749 Western blot of 721_B cell lysate.

Anti-DOK4 Antibody (aa228-258) - LS-C99155 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-DOK4 Antibody - LS-C192229 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (IHC) analysis of DOK4 pAb in paraffin-embedded Prostate cancer tissue.

Anti-DOK4 Antibody (aa11-60) IHC-plus™ - LS-B9973 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DOK4 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9973 concentration 10 ug/ml.

Anti-DOK4 Antibody - LS-C330844 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded mouse kidney using DOK4 antibody at dilution of 1:200 (200x lens).

Anti-DOK4 Antibody (C-Terminus, AP) - LS-C276852 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK4 Antibody (C-Terminus, APC) - LS-C276853 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK4 Antibody (C-Terminus, Biotin) - LS-C276854 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DOK4 Antibody (C-Terminus, FITC) - LS-C276855 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

DOK4 Antibody - NBP2-33274 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: DOK4 Antibody [NBP2-33274] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

DOK4 Polyclonal Antibody - bs-11826R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DOK4 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11826R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DOK4 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11826R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DOK4 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11826R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DOK4 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11826R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DOK4 Polyclonal Antibody, Cy3 Conjugated - bs-11826R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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