DOK4

Gene Symbol	DOK4
Entrez Gene	55715
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	docking protein 4
Other Description	IRS-5|IRS5|downstream of tyrosine kinase 4|insulin receptor substrate 5
Swissprots	Q9BTP2 Q9NVV3 O75209 Q8TEW6
Accessions	AAC24310 EAW82932 EAW82933 EAW82934 Q8TEW6 AF466369 AAL74195 AK001350 BAA91642 AK307270 AK315426 BAG37814 AW163719 BC001540 AAH01540 BC003541 AAH03541 DQ893008 ABM83934 DQ896254 ABM87253 XM_005256042 XP_005256099 XM_005256043 XP_005256100 XM_011523226 XP_011521528 NM_018110 NP_060580
Function	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. {ECO:0000250}.
Tissue Specificity	Widely expressed. High expression in skeletal muscle, heart, kidney and liver. Weaker expression in spleen, lung and small intestine, brain, heart and. Expressed in both resting and activated peripheral blood T-cells. {ECO:0000269|PubMed:12595900, ECO:0000269|PubMed:12730241}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DOK4 full length protein - ab163187 from Abcam Category Protein Source Wheat germ Species Human

Human DOK4 full length protein - ab177645 from Abcam Category Protein Source E. coli Species Human

DOK4 Antibody Blocking Peptide - LS-E22051 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DOK4 Antibody Blocking Peptide - LS-E22052 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DOK4 Antibody Blocking Peptide - LS-E9196 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DOK4 Recombinant Protein - H00055715-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

DOK4 Peptide - P2735 from Novus Biologicals Category Peptide Species Human

DOK4-Antibody-C-term-Blocking-Peptide - BP7692b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Dok4 (263-275) peptide - orb70601 from Biorbyt Category Peptide Prices $400.00 Sizes 5 mg

DOK4 Blocking Peptide - 33R-3579 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DOK4 Blocking Peptide - 33R-3481 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DOK4 protein (His tag) - 80R-3728 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

DOK4 (1-326, His-tag) - AR51415PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

DOK4 (1-326, His-tag) - AR51415PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

DOK4 - H00055715-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

DOK4, 1-326aa Human, His tag, E.coli - 01-P2595 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

DOK4 fusion protein - Ag0734 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Dok-4 (263 - 275) - 100804 from NeoScientific Category Peptide Prices $108.00, $180.00, $360.00 Sizes 5 mg, 10 mg, 25 mg

Dok-4 (130 - 145) - 100803 from NeoScientific Category Peptide Prices $108.00, $180.00 Sizes 5 mg, 10 mg

DOK4, 1-326aa Human, His tag, E.coli - GWB-ATG0C5 from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human DOK4, GST-tagged - DOK4-12129H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human DOK4, His-tagged - DOK4-5099H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human docking protein 4, His-tagged - DOK4-498H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Docking protein 4(DOK4) - CSB-YP007110HU CSB-EP007110HU CSB-BP007110HU CSB-MP007110HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DOK4, 1-326aa, Human, His tag, E.coli (Denatured) - ATGP2595 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

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